Bus Tickets from Mendoza, AR to La Serena, CL

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TodayJun 14
from US$85
TomorrowJun 15
MonJun 16
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SatJun 21

Cheap buses leaving today

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: June 14 at
    Departure city: Mendoza
    Departure location: Terminal De Omnibus Guaymallen
    Arrival time: June 14 at
    Destination city: La Serena
    Destination location: Terminal de Buses La Serena
    Operated by: CATA InternacionalCATA Internacional
    Vehicle: BusDuration:
  • Departure time: June 14 at
    Departure city: Mendoza
    Departure location: Terminal De Omnibus Guaymallen
    Arrival time: June 14 at
    Destination city: La Serena
    Destination location: Terminal de Buses La Serena
    Operated by: CATA InternacionalCATA Internacional
    Vehicle: BusDuration:

Last refresh of the prices: Last Monday at 9:39 AM -03.

Prices and availability are subject to change.

Accepted payments

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Bus Mendoza to La Serena: Trip Overview

Average Ticket PriceUS$85
Average Bus Trip Duration12h 45m
Number of daily buses1
Earliest bus departure9:15am
Distance404 km
Latest bus departure8:15pm

Mendoza to La Serena Bus

Busbud helps you find a bus from Mendoza to La Serena. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from Mendoza to La Serena will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses travelling from Mendoza to La Serena, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Mendoza, AR - La Serena, CL

  1. How long is the trip from Mendoza to La Serena by bus?

    The typical travel time from Mendoza to La Serena by bus is around 12h 45m. For the shortest travel time, select the fastest bus available, which will take you to La Serena in about 12h 45m.

  2. What is the travel distance from Mendoza to La Serena?

    The distance covered from Mendoza to La Serena is 405 km (251 miles).

  3. What are the departure and arrival locations for buses traveling from Mendoza to La Serena?

    Buses traveling this route start their trip at Mendoza Terminal, in Mendoza, and end it at Terminal de Buses La Serena, in La Serena.

  4. What is the cheapest way to go from Mendoza to La Serena?

    The least expensive option to go from Mendoza to La Serena would be going by bus. Starting at US$84, this bus is the most cost-effective option for your journey.

  5. How much does the bus ticket cost from Mendoza to La Serena?

    The bus fare from Mendoza to La Serena is approximately US$85.

  6. Is there an overnight bus from Mendoza to La Serena?

    Yes! Catch buses leaving from Mendoza until 8:15pm and reaching La Serena on the following day.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06-12
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06-13
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Today
US$78
06-15
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06-16
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06-17
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06-18
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06-19
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busbud logoThe cheapest trip from Mendoza to La Serena was searched and found on Jun 14, 2025 with a price of US$78

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mendoza to La Serena, as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Mendoza and La Serena!

Much more than a mere vehicle taking you from Mendoza to La Serena, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Mendoza to La Serena that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from Mendoza to La Serena while indulging in miles on end of beautiful scenic views.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Will you be returning to Mendoza by bus?

Bus from Mendoza to La Serena

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