How much is the bus ticket from Mendoza to La Serena?

The cheapest bus tickets from Mendoza to La Serena start from $70. The average price for this route is around $105. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Mendoza to La Serena?

The average bus trip duration from Mendoza to La Serena is 11h 45m, covering a distance of 251 miles (404 km). The quickest bus can get you there in 11h 45m and is operated by CATA Internacional .

Which bus companies service the Mendoza to La Serena route?

Several major train operators operate on this route with 1 trains available per day.

What is the earliest and latest departure time for the bus from Mendoza to La Serena?

The earliest bus departs from Mendoza to La Serena at 8:15pm. And the latest bus departs at 8:45pm.

What are the CO₂ emissions for the bus trip from Mendoza to La Serena?

A bus trip from Mendoza to La Serena generates an estimated 10 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

Bus Mendoza to La Serena from $84 | Refundable Tickets

Next bus departures

Next departures for Mendoza to La Serena on January 10
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Bus	8:16pm	Mendoza Terminal	11h 45m	8:01am	Terminal de Buses La Serena	CheapestFastest

Next departures for Mendoza to La Serena on January 13
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Bus	8:16pm	Mendoza Terminal	11h 45m	8:01am	Terminal de Buses La Serena	CheapestFastest

Last refresh of the prices: Today at 3:16 PM -03.

Get from Mendoza to La Serena

This route is served by bus only

The journey takes about 11 hours 45 minutes and with fares starting at just $70, it presents an excellent value for a comfortable ride.

1bus per day

11h 45mAverage Duration

251 milesDistance

10kgCO₂ emissions

Where are the popular stops in Mendoza and La Serena?

Stops in Mendoza

A
Mendoza Terminal
Av. Gdor. Ricardo Videla, Mendoza, Argentina
Visit page
B
Aeropuerto Mendoza
Acceso A Aeropuerto Internacional Gabrielli F. J., Las Heras, Mendoza, Argentina
Visit page
C
Hotel Hyatt
Chile 1124, 5500 Mendoza, Argentina
Visit page
D
Parada de Autobuses de Mendoza - Vallecitos
Huarpes 3124, Las Heras, Mendoza, Argentina
E
Parada de Autobuses de Mendoza - Nogoli
Nogoli 699, M5501HVC Godoy Cruz, Mendoza, Argentina
F
Vistalba 3020
Vistalba 3020, Godoy Cruz, Mendoza, Argentina

Stops in La Serena

A
Terminal de Buses La Serena
Amunátegui 107, La Serena, Región de Coquimbo, Chile
Visit page
B
Rotonda La Serena
Panamericana Norte 208, La Serena, Región de Coquimbo, Chile

Compare bus companies

CATA Internacional

4/52,109 reviews

Staff4.5

Timeliness4.1

Cleanliness4.5

Wifi1.8

Based on 2109 reviews, the company was rated 3.9 stars on Busbud. Travelers were especially satisfied with the departure location and the staff but often complained with the wifi. CATA Internacional ticket prices on this trip start at $70

CATA Internacional Mendoza La Serena recent customer reviews

It would be better if we didn't have to print tickets off to board the bus- this is quite difficult when traveling

Wendy L.

April 23, 2017

The bus broke down for 5 hours we waited for another one to pick us up. No explanation from the staff (they just laughed). At the terminal once we arrived they had no compensation, no apology nothing ! Terrible journey and won't book that company again .

Rachel H.

March 13, 2017

CL bus companies:FlixBus, BlaBlaCar Bus, Greyhound, ALSA, Intercape, Trenitalia, Big Sky

Frequently asked questions about traveling from Mendoza, AR to La Serena, CL by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Mendoza to La Serena?
The cheapest bus tickets from Mendoza to La Serena start from $70. The average price for this route is around $105. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Mendoza to La Serena?
The average bus trip duration from Mendoza to La Serena is 11h 45m, covering a distance of 251 miles (404 km). The quickest bus can get you there in 11h 45m and is operated by CATA Internacional.
Which bus companies service the Mendoza to La Serena route?
Several major train operators operate on this route with 1 trains available per day.
What is the earliest and latest departure time for the bus from Mendoza to La Serena?
The earliest bus departs from Mendoza to La Serena at 8:15pm. And the latest bus departs at 8:45pm.
What are the CO₂ emissions for the bus trip from Mendoza to La Serena?
A bus trip from Mendoza to La Serena generates an estimated 10 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

01/06

$97

01/07

No data

Today

$98

01/09

No data

01/10

$97

01/11

No data

01/12

No data

01/13

$97

The cheapest trip from Mendoza, AR to La Serena, CL was searched and found on Jan 6, 2026 with a price of $97

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mendoza, AR to La Serena, CL, as early as possible.

You can expect to pay from $97 to $117 for a bus ticket from Mendoza, AR to La Serena, CL based on the last 2 days. You can expect to find the cheapest price for the trip at $97 which is on 2026-01-10.