Bus Tickets from Midland, TX, US to San Antonio, US

Next departures

Next departures for Midland to San Antonio on October 9
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc. + Valley Transit
Farm to Market, Midland
San Antonio Bus StationCheapest
Greyhound Lines, Inc. + Valley Transit
Farm to Market, Midland
San Antonio Bus StationFastest
Greyhound Lines, Inc. + Greyhound Lines Mexico
Farm to Market, Midland
San Antonio Bus StationNo tags

Last refresh of the prices: Yesterday at 10:32 AM CDT.

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Bus Midland, TX, US to San Antonio, US: Trip Overview

Average Ticket PriceUS$154
Average Bus Trip Duration12h 50m
Number of daily buses3
Earliest bus departure12:20am
Distance451 km
Latest bus departure8:35pm

Midland to San Antonio Bus

Busbud helps you find a bus from Midland to San Antonio. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make it our job to connect you with the most dependable bus companies that cover bus service from Midland to San Antonio.

From cheap bus tickets to more luxurious buses travelling from Midland to San Antonio, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Midland, TX, US - San Antonio, US

  1. What is the distance between Midland and San Antonio?

    The distance between Midland and San Antonio is approximately 447 km (278 miles).

  2. What are the departure and arrival locations for buses traveling from Midland to San Antonio?

    Buses departing from Midland Bus Stop in Midland will take you to San Antonio Bus Station in San Antonio.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
10-06
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10-07
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Today
US$21
10-09
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10-10
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10-11
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10-12
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busbud logoThe cheapest trip from Midland, TX, US to San Antonio, US was searched and found on Oct 8, 2025 with a price of US$21

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Midland, TX, US to San Antonio, US, as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Midland and San Antonio!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Midland to San Antonio.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Midland to San Antonio that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from Midland to San Antonio while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Will you be returning to Midland, TX, US by bus?

Bus from San Antonio, US to Midland, TX, US

Why choose Busbud?

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