Bus Tickets from Milano to Palermo

Next departures

Next departures for Milano to Palermo on October 24
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Autoservizi Salemi
Lampugnano
Terminal Bus PalermoCheapest
Autoservizi Salemi
Milan San Donato Bus Station
Terminal Bus PalermoFastest

Last refresh of the prices: Today at 8:19 AM CEST.

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Compare 2 ways to go from Milano to Palermo

busbud logoWe recommend carpooling

Among the sustainable travel choices, the carpool stands out as a good way to reach Palermo. The journey takes about 16 hours 40 minutes, and with fares starting at just US$79, it presents an excellent value for a comfortable ride.

1carpool per day
16h 40mAverage Duration
887 kmDistance
37kgCO₂ emissions
Bus
Average PriceUS$40 - US$241Average Duration1d 2h
22kg CO₂e
Carpool
Average PriceUS$79 - US$141Average Duration16h 40m
37kg CO₂e

Bus Milano to Palermo: Trip Overview

Average Ticket PriceUS$105
Average Bus Trip Duration1d 2h
Number of daily buses13
Earliest bus departure3:05am
Distance885 km
Latest bus departure10:45pm

Milano to Palermo Bus

Busbud helps you find a bus from Milano to Palermo. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Milano to Palermo from the most reliable bus companies operating this trip.

Discover how much the bus trip from Milano to Palermo will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Milano - Palermo

  1. What is the travel distance from Milano to Palermo?

    It's about 888 km (551 miles) from Milano to Palermo.

  2. What are the departure and arrival locations for buses traveling from Milano to Palermo?

    Buses traveling this route start their trip at Lampugnano, in Milano, and end it at Terminal Bus Palermo, in Palermo.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
10-21
US$110
10-22
US$184
Today
US$97
10-24
US$96
10-25
US$70
10-26
US$74
10-27
US$97
10-28
US$72
busbud logoThe cheapest trip from Milano to Palermo was searched and found on Oct 25, 2025 with a price of US$70

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Milano to Palermo, as early as possible.

You can expect to pay from US$70 to US$202 for a bus ticket from Milano to Palermo based on the last 2 days. You can expect to find the cheapest price for the trip at US$70 which is on 2025-10-25.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Milano and Palermo!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Milano to Palermo, get comfy and count the stars.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Milano to Palermo will emit less CO2 than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Milano to Palermo.

Did you know?

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

What's the cheapest way to go from Milano to Palermo?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Milano by bus?

Bus from Palermo to Milano

Why choose Busbud?

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