Bus Tickets from Milan to Palermo

Find affordable bus tickets from Milan to Palermo with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.
TodayJul 14
from US$122
TomorrowJul 15
from US$117
WedJul 16
from US$117
ThuJul 17
from US$117
FriJul 18
from US$117
SatJul 19
SunJul 20
from US$117
MonJul 21
from US$117

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: July 15 at
    Departure city: Milano
    Departure location: Lampugnano
    Arrival time: July 16 at
    Destination city: Palermo
    Destination location: Terminal Bus Palermo
    Operated by: Autoservizi SalemiAutoservizi Salemi
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: July 15 at
    Departure city: Milano
    Departure location: Milan San Donato Bus Station
    Arrival time: July 16 at
    Destination city: Palermo
    Destination location: Terminal Bus Palermo
    Operated by: Autoservizi SalemiAutoservizi Salemi
    Vehicle: BusDuration:
  • Departure time: July 15 at
    Departure city: Milano
    Departure location: Milan San Donato Bus Station
    Arrival time: July 16 at
    Destination city: Palermo
    Destination location: Terminal Bus Palermo
    Operated by: Autoservizi SalemiAutoservizi Salemi
    Vehicle: BusDuration:
  • Departure time: July 15 at
    Departure city: Milano
    Departure location: Lampugnano bus station
    Arrival time: July 16 at
    Destination city: Palermo
    Destination location: Terminal Bus Palermo
    Operated by: Flixbus Flixbus
    Vehicle: BusDuration:
  • Departure time: July 15 at
    Departure city: Milano
    Departure location: Lampugnano bus station
    Arrival time: July 16 at
    Destination city: Palermo
    Destination location: Terminal Bus Palermo
    Operated by: Flixbus Flixbus
    Vehicle: BusDuration:

Last refresh of the prices: Today at 3:12 AM CEST.

Prices and availability are subject to change.

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from Milan to Palermo

Bus
Average PriceUS$56 - US$295Average Duration1d 1h
22kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Carpool
Average PriceUS$71 - US$143Average Duration16h 40m
37kg CO₂e4 out of 5 stars
Fastest
busbud logoBusbud recommends carpooling from Milan to Palermo

Among the sustainable travel choices, the carpool stands out as a good way to reach Palermo. The journey takes about 16 hours 40 minutes, and with fares starting at just US$71, it presents an excellent value for a comfortable ride.

1carpool per day
16h 40mAverage Duration
US$71Cheapest ticket
37kgCO₂ emissions

Bus Milano to Palermo: Trip Overview

Average Ticket PriceUS$124
Average Bus Trip Duration1d 1h
Number of daily buses17
Earliest bus departure12:30am
Distance894 km
Latest bus departure11:50pm

Milan to Palermo Bus

Busbud helps you find a bus from Milan to Palermo. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Milan to Palermo from the most reliable bus companies operating this trip.

Discover how much the bus trip from Milan to Palermo will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Milan - Palermo

  1. What is the travel distance from Milan to Palermo?

    It's about 888 km (551 miles) from Milan to Palermo.

  2. What are the departure and arrival locations for buses traveling from Milan to Palermo?

    Buses traveling this route start their trip at Piazza I Maggio, 1, in Milan, and end it at Terminal Bus Palermo, in Palermo.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
07-12
US$106
07-13
US$119
Today
US$110
07-15
US$106
07-16
US$106
07-17
US$106
07-18
US$106
07-19
US$106
busbud logoThe cheapest trip from Milano to Palermo was searched and found on Jul 17, 2025 with a price of US$106

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Milano to Palermo, as early as possible.

You can expect to pay from US$106 to US$239 for a bus ticket from Milano to Palermo based on the last 2 days. You can expect to find the cheapest price for the trip at US$106 which is on 2025-07-17.

Usually Flixbus (IT) will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Milan and Palermo!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Milan to Palermo, get comfy and count the stars.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Milan to Palermo will emit less CO2 than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Milan to Palermo.

Did you know?

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Will you be returning to Milano by bus?

Bus from Milano to Palermo

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

People from around the world trust Busbud

‌

Popular Buses Connecting Milano

Buses Leaving from Milano

Buses Going to Milano

Popular Buses Connecting Palermo

Buses Leaving from Palermo

Buses Going to Palermo