Bus Tickets from Milwaukee to St. Louis

Next departures

Next departures for Milwaukee to St. Louis on October 17
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus
Goerke's Corners Park & Ride (Brookfield)
Gateway StationCheapest
Greyhound Lines, Inc. + FlixBus
Milwaukee Bus Station, St. Paul & N6th road.
Gateway StationFastest
Greyhound Lines, Inc.
Milwaukee Bus Station, St. Paul & N6th road.
Gateway StationNo tags
FlixBus
Milwaukee Bus Station, St. Paul & N6th road.
Gateway StationNo tags
FlixBus
Milwaukee Bus Station, St. Paul & N6th road.
Gateway StationNo tags

Last refresh of the prices: Today at 8:08 AM CDT.

Accepted payments

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Compare 2 ways to go from Milwaukee to St. Louis

Bus
Average PriceUS$40 - US$152Average Duration11h 10m
13kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average PriceUS$51 - US$131Average Duration8h 25m
48kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the train from Milwaukee to St. Louis

Among the sustainable travel choices, the train stands out as a good way to reach St. Louis. The journey takes about 8 hours 25 minutes, and with fares starting at just US$51, it presents an excellent value for a comfortable ride.

9train per day
8h 25mAverage Duration
US$51Cheapest ticket
48kgCO₂ emissions

Bus Milwaukee to St. Louis: Trip Overview

Average Ticket PriceUS$59
Average Bus Trip Duration11h 10m
Number of daily buses7
Earliest bus departure3:20am
Distance519 km
Latest bus departure7:35pm

Milwaukee to St. Louis Bus

With Busbud, comparing and booking tickets for a bus from Milwaukee to St. Louis is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from Milwaukee to St. Louis.

Discover how much the bus trip from Milwaukee to St. Louis will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Milwaukee - St. Louis

  1. What is the travel distance from Milwaukee to St. Louis?

    The distance covered from Milwaukee to St. Louis is 528 km (328 miles).

  2. What are the departure and arrival locations for buses traveling from Milwaukee to St. Louis?

    Buses traveling this route start their trip at Milwaukee Airport, in Milwaukee, and end it at Gateway Station, in St. Louis.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
10-10
US$57
10-11
US$83
Today
US$92
10-13
US$60
10-14
US$78
10-15
US$52
10-16
US$52
10-17
US$60
busbud logoThe cheapest trip from Milwaukee to St. Louis was searched and found on Oct 15, 2025 with a price of US$52

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Milwaukee to St. Louis, as early as possible.

You can expect to pay from US$52 to US$119 for a bus ticket from Milwaukee to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at US$52 which is on 2025-10-15.

Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Milwaukee to St. Louis.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Milwaukee to St. Louis.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Milwaukee to St. Louis will emit less CO2 than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Milwaukee to St. Louis.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

What's the cheapest way to go from Milwaukee to St. Louis?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Milwaukee by bus?

Bus from St. Louis to Milwaukee

You can also go to St. Louis by train

Train from Milwaukee to St. Louis

Why choose Busbud?

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