How much is the bus ticket from Milwaukee to St. Louis?

The cheapest bus tickets from Milwaukee to St. Louis start from $47. The average price for this route is around $65. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Milwaukee to St. Louis?

The average bus trip duration from Milwaukee to St. Louis is 11h 15m, covering a distance of 322 miles (519 km). The quickest bus can get you there in 8h 50m and is operated by FlixBus .

Which bus companies service the Milwaukee to St. Louis route?

Several major bus companies operate on this route with 7 buses available per day, including services from FlixBus , Greyhound .

What is the earliest and latest departure time for the bus from Milwaukee to St. Louis?

The earliest bus departs from Milwaukee to St. Louis at 3:20am. And the latest bus departs at 9:35pm.

What are the CO₂ emissions for the bus trip from Milwaukee to St. Louis?

A bus trip from Milwaukee to St. Louis generates an estimated 13 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

What is the best bus company from Milwaukee to St. Louis?

According to Busbud customers, the highest-rated bus company on this route is FlixBus , with an average rating of 3.5 out of 5 stars based on 11380 reviews.

Which bus company has the best Wi-Fi from Milwaukee to St. Louis?

Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

Which bus company has the most timely service from Milwaukee to St. Louis?

According to Busbud traveller reviews, the most timely bus company on this route is FlixBus , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from Milwaukee to St. Louis?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus , with a cleanliness rating of 4.1 out of 5 stars.

Bus Milwaukee to St. Louis from $52 | Refundable Tickets

Next bus departures

Next departures for Milwaukee to St. Louis on December 1
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	7:15pm	Milwaukee Bus Station, St. Paul & N6th road.	11h 10m	6:25am	Gateway Station	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus	7:35pm	Milwaukee Mitchell MKE Airport	10h 50m	6:25am	Gateway Station	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	6:45pm	Goerke's Corners Park & Ride (Brookfield)	11h 40m	6:25am	Gateway Station	No tags

Next departures for Milwaukee to St. Louis on December 2
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	3:40pm	Milwaukee Mitchell MKE Airport	14h 45m	6:25am	Gateway Station	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus	12:10pm	Milwaukee Mitchell MKE Airport	11h 15m	11:25pm	Gateway Station	Fastest
	Bus	3:20am	Milwaukee Bus Station, St. Paul & N6th road.	12h	3:20pm	Gateway Station	No tags
FlixBus + Greyhound Lines, Inc.	Bus	11:50am	Milwaukee Bus Station, St. Paul & N6th road.	11h 35m	11:25pm	Gateway Station	No tags
FlixBus + Greyhound Lines, Inc.	Bus	3:20pm	Milwaukee Bus Station, St. Paul & N6th road.	15h 5m	6:25am	Gateway Station	No tags

Next departures for Milwaukee to St. Louis on December 4
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	9:20am	Milwaukee Mitchell MKE Airport	13h 50m	11:10pm	Gateway Station	Cheapest
Greyhound Lines, Inc. + FlixBus	Bus	6:30am	Milwaukee Bus Station, St. Paul & N6th road.	9h 15m	3:45pm	Gateway Station	Fastest
	Bus	3:20am	Milwaukee Bus Station, St. Paul & N6th road.	12h	3:20pm	Gateway Station	No tags
	Bus	9:00am	Milwaukee Bus Station, St. Paul & N6th road.	14h 10m	11:10pm	Gateway Station	No tags
	Bus	7:15pm	Milwaukee Bus Station, St. Paul & N6th road.	11h 10m	6:25am	Gateway Station	No tags

Next departures for Milwaukee to St. Louis on December 5
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	12:10pm	Milwaukee Mitchell MKE Airport	11h	11:10pm	Gateway Station	Cheapest
Greyhound Lines, Inc. + FlixBus	Bus	6:30am	Milwaukee Bus Station, St. Paul & N6th road.	9h 15m	3:45pm	Gateway Station	Fastest
	Bus	3:20am	Milwaukee Bus Station, St. Paul & N6th road.	12h	3:20pm	Gateway Station	No tags
	Bus	11:50am	Milwaukee Bus Station, St. Paul & N6th road.	11h 20m	11:10pm	Gateway Station	No tags
	Bus	7:15pm	Milwaukee Bus Station, St. Paul & N6th road.	11h 10m	6:25am	Gateway Station	No tags

Next departures for Milwaukee to St. Louis on December 6
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	11:50am	Milwaukee Bus Station, St. Paul & N6th road.	11h 20m	11:10pm	Gateway Station	Cheapest
Greyhound Lines, Inc. + FlixBus	Bus	6:30am	Milwaukee Bus Station, St. Paul & N6th road.	9h 15m	3:45pm	Gateway Station	Fastest
	Bus	3:20am	Milwaukee Bus Station, St. Paul & N6th road.	12h	3:20pm	Gateway Station	No tags
	Bus	7:15pm	Milwaukee Bus Station, St. Paul & N6th road.	11h 10m	6:25am	Gateway Station	No tags
	Bus	12:10pm	Milwaukee Mitchell MKE Airport	11h	11:10pm	Gateway Station	No tags

Next departures for Milwaukee to St. Louis on December 7
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	7:35pm	Milwaukee Mitchell MKE Airport	10h 50m	6:25am	Gateway Station	Cheapest
Greyhound Lines, Inc. + FlixBus	Bus	6:30am	Milwaukee Bus Station, St. Paul & N6th road.	9h 15m	3:45pm	Gateway Station	Fastest
	Bus	3:20am	Milwaukee Bus Station, St. Paul & N6th road.	12h	3:20pm	Gateway Station	No tags
	Bus	11:50am	Milwaukee Bus Station, St. Paul & N6th road.	11h 20m	11:10pm	Gateway Station	No tags
	Bus	7:15pm	Milwaukee Bus Station, St. Paul & N6th road.	11h 10m	6:25am	Gateway Station	No tags

Next departures for Milwaukee to St. Louis on December 8
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	3:20am	Milwaukee Bus Station, St. Paul & N6th road.	12h	3:20pm	Gateway Station	Cheapest
Greyhound Lines, Inc. + FlixBus	Bus	6:30am	Milwaukee Bus Station, St. Paul & N6th road.	9h 15m	3:45pm	Gateway Station	Fastest
	Bus	11:50am	Milwaukee Bus Station, St. Paul & N6th road.	11h 20m	11:10pm	Gateway Station	No tags
FlixBus + Greyhound Lines, Inc.	Bus	7:15pm	Milwaukee Bus Station, St. Paul & N6th road.	11h 10m	6:25am	Gateway Station	No tags
	Bus	12:10pm	Milwaukee Mitchell MKE Airport	11h	11:10pm	Gateway Station	No tags

Last refresh of the prices: Yesterday at 4:38 PM CST.

Compare 2 ways to go from Milwaukee to St. Louis

We recommend taking the train

Among the sustainable travel choices, the train stands out as the good way to reach St. Louis. The journey takes about 8 hours 25 minutes and with fares starting at just $51, it presents an excellent value for a comfortable ride.

9train per day

8h 25mAverage Duration

327 milesDistance

48kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$47 - $184	Average Duration11h 15m	CO₂ emissions 13kg CO₂e
Train	Average Price$51 - $342	Average Duration8h 25m	CO₂ emissions 48kg CO₂e

Where are the popular stops in Milwaukee and St. Louis?

Stops in Milwaukee

A
Milwaukee Airport
Visit page
B
Intermodal Station
433 W St Paul Ave, Milwaukee, WI 53203, USA
Visit page
C
S Cesar Chavez
1016 S Cesar E Chavez Dr, Milwaukee, WI 53204, USA

Stops in St. Louis

A
Gateway Station
430 S 15th St, St Louis, MO 63103
Visit page

Compare bus companies

FlixBus

3.5/511,488 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Greyhound

3.5/587,410 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about traveling from Milwaukee to St. Louis by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Milwaukee to St. Louis?
The cheapest bus tickets from Milwaukee to St. Louis start from $47. The average price for this route is around $65. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Milwaukee to St. Louis?
The average bus trip duration from Milwaukee to St. Louis is 11h 15m, covering a distance of 322 miles (519 km). The quickest bus can get you there in 8h 50m and is operated by FlixBus.
Which bus companies service the Milwaukee to St. Louis route?
Several major bus companies operate on this route with 7 buses available per day, including services from FlixBus, Greyhound.
What is the earliest and latest departure time for the bus from Milwaukee to St. Louis?
The earliest bus departs from Milwaukee to St. Louis at 3:20am. And the latest bus departs at 9:35pm.
What are the CO₂ emissions for the bus trip from Milwaukee to St. Louis?
A bus trip from Milwaukee to St. Louis generates an estimated 13 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Milwaukee to St. Louis?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 11380 reviews.
Which bus company has the best Wi-Fi from Milwaukee to St. Louis?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Milwaukee to St. Louis?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Milwaukee to St. Louis?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/29

$148

11/30

$124

Today

$119

12/02

$163

12/03

$61

12/04

$57

12/05

$65

12/06

$85

The cheapest trip from Milwaukee to St. Louis was searched and found on Dec 4, 2025 with a price of $57

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Milwaukee to St. Louis, as early as possible.

You can expect to pay from $57 to $214 for a bus ticket from Milwaukee to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $57 which is on 2025-12-04.