How much is the bus ticket from Mobile to San Diego?

The cheapest bus tickets from Mobile to San Diego start from $249. The average price for this route is around $435. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Mobile to San Diego?

The average bus travel time from Mobile to San Diego is 2d 2h, covering a distance of 2756 km. The quickest bus can get you there in 1d 21h and is operated by Greyhound .

Which bus companies service the Mobile to San Diego route?

Several major bus companies operate on this route with 8 buses available per day.

What are the earliest and latest departure times for the bus from Mobile to San Diego?

The earliest bus departs from Mobile to San Diego at 5:55am. And the latest bus departs at 10:30pm.

What are the CO₂ emissions for the bus trip from Mobile to San Diego?

A bus trip from Mobile to San Diego generates an estimated 69 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.

Bus Mobile to San Diego from $346 | Refundable Tickets

Next bus departures

Next departures for Mobile to San Diego on December 5
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	10:30pm	Greyhound Station	1d 21h	5:45pm	Greyhound Bus Stop	CheapestFastest
Greyhound Lines, Inc. + FlixBus	Bus	10:30pm	Greyhound Station	2d 17h	2:10pm	San Diego (Old Town-FlixBus)	No tags
Greyhound Lines, Inc. + FlixBus	Bus	10:30pm	Greyhound Station	2d 1h	9:45pm	UCSD Health La Jolla Station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	10:30pm	Greyhound Station	2d 1h	10:15pm	Downtown SD (Seaport)	No tags

Next departures for Mobile to San Diego on December 6
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	10:30pm	Greyhound Station	2d 1h	10:15pm	Downtown SD (Seaport)	Cheapest
	Bus	10:30pm	Greyhound Station	1d 21h	5:45pm	Greyhound Bus Stop	Fastest
Greyhound Lines, Inc. + FlixBus	Bus	1:50pm	Greyhound Station	2d 2h	2:10pm	San Diego (Old Town-FlixBus)	No tags
	Bus	5:55am	Greyhound Station	2d 7h	11:45am	Greyhound Bus Stop	No tags
Greyhound Lines, Inc. + FlixBus	Bus	5:55am	Greyhound Station	2d 5h	9:40am	UCSD Health La Jolla Station	No tags

Next departures for Mobile to San Diego on December 7
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	10:30pm	Greyhound Station	1d 21h	5:45pm	Greyhound Bus Stop	CheapestFastest
Greyhound Lines, Inc. + FlixBus	Bus	8:30am	Greyhound Station	2d 11h	6:10pm	San Diego (Old Town-FlixBus)	No tags
	Bus	5:55am	Greyhound Station	2d 7h	11:45am	Greyhound Bus Stop	No tags
Greyhound Lines, Inc. + FlixBus	Bus	5:55am	Greyhound Station	2d 12h	3:55pm	UCSD Health La Jolla Station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	10:30pm	Greyhound Station	2d 1h	9:45pm	UCSD Health La Jolla Station	No tags

Next departures for Mobile to San Diego on December 8
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	10:30pm	Greyhound Station	2d 1h	9:45pm	UCSD Health La Jolla Station	CheapestFastest
Greyhound Lines, Inc. + FlixBus	Bus	8:30am	Greyhound Station	2d 11h	6:10pm	San Diego (Old Town-FlixBus)	No tags
	Bus	5:55am	Greyhound Station	2d 7h	11:45am	Greyhound Bus Stop	No tags
Greyhound Lines, Inc. + FlixBus	Bus	10:30pm	Greyhound Station	2d 17h	2:10pm	San Diego (Old Town-FlixBus)	No tags
	Bus	10:30pm	Greyhound Station	2d 3h	11:50pm	Greyhound Bus Stop	No tags

Next departures for Mobile to San Diego on December 9
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	1:50pm	Greyhound Station	2d 1h	1:40pm	UCSD Health La Jolla Station	Cheapest
Greyhound Lines, Inc. + FlixBus	Bus	10:30pm	Greyhound Station	2d 1h	9:45pm	UCSD Health La Jolla Station	Fastest
Greyhound Lines, Inc. + FlixBus	Bus	1:50pm	Greyhound Station	2d 2h	2:10pm	San Diego (Old Town-FlixBus)	No tags
	Bus	5:55am	Greyhound Station	2d 7h	11:45am	Greyhound Bus Stop	No tags
Greyhound Lines, Inc. + FlixBus	Bus	10:30pm	Greyhound Station	2d 17h	2:10pm	San Diego (Old Town-FlixBus)	No tags

Next departures for Mobile to San Diego on December 10
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	5:55am	Greyhound Station	2d 7h	11:45am	Greyhound Bus Stop	Cheapest
	Bus	10:30pm	Greyhound Station	1d 21h	5:45pm	Greyhound Bus Stop	Fastest
Greyhound Lines, Inc. + FlixBus	Bus	1:50pm	Greyhound Station	2d 2h	2:10pm	San Diego (Old Town-FlixBus)	No tags
Greyhound Lines, Inc. + FlixBus	Bus	10:30pm	Greyhound Station	2d 17h	2:10pm	San Diego (Old Town-FlixBus)	No tags
Greyhound Lines, Inc. + FlixBus	Bus	5:55am	Greyhound Station	2d 5h	9:40am	UCSD Health La Jolla Station	No tags

Next departures for Mobile to San Diego on December 11
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	10:30pm	Greyhound Station	2d 1h	9:45pm	UCSD Health La Jolla Station	Cheapest
	Bus	10:30pm	Greyhound Station	1d 21h	5:45pm	Greyhound Bus Stop	Fastest
Greyhound Lines, Inc. + FlixBus	Bus	1:50pm	Greyhound Station	2d 2h	2:10pm	San Diego (Old Town-FlixBus)	No tags
	Bus	5:55am	Greyhound Station	2d 7h	11:45am	Greyhound Bus Stop	No tags
Greyhound Lines, Inc. + FlixBus	Bus	10:30pm	Greyhound Station	2d 17h	2:10pm	San Diego (Old Town-FlixBus)	No tags

Last refresh of the prices: Last Sunday at 1:58 PM CST.

Get from Mobile to San Diego

This route is served by bus only

The journey takes about 2 days, 2 hours 20 minutes, and with fares starting at just $249, it presents an excellent value for a comfortable ride.

8bus per day

2d 2hAverage Duration

2756 kmDistance

69kgCO₂ emissions

Where are the popular stops in Mobile and San Diego?

Stops in Mobile

A
Greyhound Station
2545 Government Blvd, Mobile, AL 36606
Visit page

Stops in San Diego

A
Mission Valley Sheraton
1433 Camino del Rio S, San Diego, CA 92108, USA
B
Old Town Courtyard Marriot
2435 Jefferson St, San Diego, CA 92110, USA
C
Downtown Holiday Inn
1617 1st Ave, San Diego, CA 92101, USA
D
Greyhound Station
1313 National Ave, San Diego, CA 92101, USA
E
Market St. & Park Blvd
601 Park Boulevard, San Diego, CA 92101, USA
F
San Ysidro McDonald's
727 E San Ysidro Blvd, San Diego, CA 92173, USA

Compare bus companies

Greyhound

3.5/587,415 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Based on 87415 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $254

US Bus Companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Big Sky

Frequently asked questions about travelling from Mobile to San Diego, CA, US by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Mobile to San Diego?
The cheapest bus tickets from Mobile to San Diego start from $249. The average price for this route is around $435. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Mobile to San Diego?
The average bus travel time from Mobile to San Diego is 2d 2h, covering a distance of 2756 km. The quickest bus can get you there in 1d 21h and is operated by Greyhound.
Which bus companies service the Mobile to San Diego route?
Several major bus companies operate on this route with 8 buses available per day.
What are the earliest and latest departure times for the bus from Mobile to San Diego?
The earliest bus departs from Mobile to San Diego at 5:55am. And the latest bus departs at 10:30pm.
What are the CO₂ emissions for the bus trip from Mobile to San Diego?
A bus trip from Mobile to San Diego generates an estimated 69 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

12-03

$363

12-04

No data

Today

$346

12-06

$388

12-07

$422

12-08

$464

12-09

$424

12-10

$478

The cheapest trip from Mobile to San Diego, CA, US was searched and found on Dec 5, 2025 with a price of $346

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mobile to San Diego, CA, US, as early as possible.

You can expect to pay from $346 to $501 for a bus ticket from Mobile to San Diego, CA, US based on the last 2 days. You can expect to find the cheapest price for the trip at $388 which is on 2025-12-06.