Bus Tickets from Mobile to San Diego, CA, US

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TodayJun 25
from $385
TomorrowJun 26
FriJun 27
SatJun 28
SunJun 29
MonJun 30
TueJul 1
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Cheap buses leaving today

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: June 25 at
    Departure city: Mobile
    Departure location: Greyhound Station
    Arrival time: June 27 at
    Destination city: San Diego
    Destination location: San Diego (Old Town-FlixBus)
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: June 25 at
    Departure city: Mobile
    Departure location: Greyhound Station
    Arrival time: June 27 at
    Destination city: San Diego
    Destination location: Greyhound Bus Stop
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 25 at
    Departure city: Mobile
    Departure location: Greyhound Station
    Arrival time: June 28 at
    Destination city: San Diego
    Destination location: San Diego (Old Town-FlixBus)
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: June 25 at
    Departure city: Mobile
    Departure location: Greyhound Station
    Arrival time: June 27 at
    Destination city: San Diego
    Destination location: Greyhound Bus Stop
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 25 at
    Departure city: Mobile
    Departure location: Greyhound Station
    Arrival time: June 27 at
    Destination city: San Diego
    Destination location: UCSD Health La Jolla Station
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:

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Bus Mobile to San Diego: Trip Overview

Average ticket price$442
Average bus trip duration2d 5h
Number of daily buses13
Earliest bus departure2:40am
Distance1706 miles (2751 km)
Latest bus departure10:55pm

Mobile to San Diego Bus

Busbud helps you find a bus from Mobile to San Diego. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make it our job to connect you with the most dependable bus companies that cover bus service from Mobile to San Diego.

Whether it is cheap bus tickets or more luxurious buses going to San Diego from Mobile, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip Mobile - San Diego, CA, US

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06/23
No data
06/24
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Today
$338
06/26
No data
06/27
No data
06/28
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06/29
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06/30
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busbud logoThe cheapest trip from Mobile to San Diego was searched and found on Jun 25, 2025 with a price of $338

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mobile to San Diego, as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Mobile and San Diego!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Mobile to San Diego.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Mobile to San Diego.

Tune out to the fine sounds of your best music playlist on your bus trip from Mobile to San Diego while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Will you be returning to Mobile by bus?

Bus from Mobile to San Diego

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