- Myrtle Beach to Knoxville buses
Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
![]() | Bus | Bus Station | Knoxville Bus Station | No tags | ||||
![]() | Bus | Bus Station | Knoxville Bus Station | No tags | ||||
![]() | Bus | Bus Station | Knoxville Bus Station | No tags | ||||
![]() | Bus | Bus Station | Knoxville Bus Station | No tags | ||||
![]() | Bus | Bus Station | Knoxville Bus Station | No tags |
Get from Myrtle Beach to Knoxville
The journey takes about 1 day, 9 hours 5 minutes, and with fares starting at just $185, it presents an excellent value for a comfortable ride.
Where are the popular stops in Myrtle Beach and Knoxville?
Stops in Knoxville
- AKnoxville Area Transit Bus Stop, 100 Kirkwood St, Knoxville, TN 37914, USA
Compare bus companies
Based on 87418 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $185
Frequently asked questions about travelling from Myrtle Beach to Knoxville, TN by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Myrtle Beach to Knoxville?
The cheapest bus tickets from Myrtle Beach to Knoxville start from $185. The average price for this route is around $230. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Myrtle Beach to Knoxville?
The average bus travel time from Myrtle Beach to Knoxville is 1d 9h, covering a distance of 523 km. The quickest bus can get you there in 1d 9h and is operated by Greyhound.
Which bus companies service the Myrtle Beach to Knoxville route?
Several major bus companies operate on this route with 1 buses available per day.
What are the earliest and latest departure times for the bus from Myrtle Beach to Knoxville?
The earliest bus departs from Myrtle Beach to Knoxville at 12:45pm. And the latest bus departs at 12:45pm.
What are the CO₂ emissions for the bus trip from Myrtle Beach to Knoxville?
A bus trip from Myrtle Beach to Knoxville generates an estimated 13 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.






