Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Bus Station | Knoxville Bus Station | No tags | ||||
| Bus | Bus Station | Knoxville Bus Station | No tags | ||||
| Bus | Bus Station | Knoxville Bus Station | No tags | ||||
| Bus | Bus Station | Knoxville Bus Station | No tags | ||||
| Bus | Bus Station | Knoxville Bus Station | No tags |
Get from Myrtle Beach to Knoxville
The journey takes about 1 day, 9 hours 5 minutes and with fares starting at just $131, it presents an excellent value for a comfortable ride.
Where are the popular stops in Myrtle Beach and Knoxville?
Stops in Knoxville
- AKnoxville Area Transit Bus Stop, 100 Kirkwood St, Knoxville, TN 37914, USA
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Myrtle Beach to Knoxville, TN by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Myrtle Beach to Knoxville?
The cheapest bus tickets from Myrtle Beach to Knoxville start from $131. The average price for this route is around $162. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Myrtle Beach to Knoxville?
The average bus trip duration from Myrtle Beach to Knoxville is 1d 9h, covering a distance of 325 miles (523 km). The quickest bus can get you there in 1d 9h and is operated by Greyhound.
Which bus companies service the Myrtle Beach to Knoxville route?
Several major train operators operate on this route with 1 trains available per day.
What is the earliest and latest departure time for the bus from Myrtle Beach to Knoxville?
The earliest bus departs from Myrtle Beach to Knoxville at 12:45pm. And the latest bus departs at 12:45pm.
What are the CO₂ emissions for the bus trip from Myrtle Beach to Knoxville?
A bus trip from Myrtle Beach to Knoxville generates an estimated 13 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Top traveled bus routes
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Popular bus departures from Myrtle Beach
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