Bus Tickets from Panama City, US to San Jose, US

Next departures

Next departures for Panama City to San Jose on October 13
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.
Panama City Beach Station
Diridon StationCheapestFastest

Last refresh of the prices: Last Friday at 11:38 PM CDT.

Accepted payments

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Bus Panama City, US to San Jose, US: Trip Overview

Average Ticket PriceUS$253
Average Bus Trip Duration2d 10h
Number of daily buses1
Earliest bus departure9:10pm
Distance3411 km

Panama City to San Jose Bus

Busbud helps you find a bus from Panama City to San Jose. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Panama City to San Jose from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses travelling from Panama City to San Jose, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Panama City, US - San Jose, US

  1. What is the travel distance from Panama City to San Jose?

    The distance between Panama City and San Jose is approximately 3425 km (2124 miles).

  2. What are the departure and arrival locations for buses traveling from Panama City to San Jose?

    Buses departing from Panama City Greyhound Bus Station in Panama City will take you to Diridon Station in San Jose.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
10-10
US$246
10-11
No data
Today
US$443
10-13
US$285
10-14
US$199
10-15
US$305
10-16
No data
10-17
No data
busbud logoThe cheapest trip from Panama City, US to San Jose, US was searched and found on Oct 14, 2025 with a price of US$199

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Panama City, US to San Jose, US, as early as possible.

You can expect to pay from US$199 to US$443 for a bus ticket from Panama City, US to San Jose, US based on the last 2 days. You can expect to find the cheapest price for the trip at US$199 which is on 2025-10-14.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Panama City and San Jose!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Panama City to San Jose, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Panama City to San Jose that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Panama City to San Jose.

Did you know?

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Will you be returning to Panama City, US by bus?

Bus from San Jose, US to Panama City, US

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

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