Bus Tickets from Panama City, US to San Jose, US

Next departures

Next departures for Panama City to San Jose on October 18
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.
Panama City Beach Station
Diridon StationCheapestFastest

Last refresh of the prices: Yesterday at 3:13 PM CDT.

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Bus Panama City, US to San Jose, US: Trip Overview

Average ticket price$292
Average bus trip duration2d 10h
Number of daily buses1
Earliest bus departure9:10pm
Distance2115 miles (3411 km)
Latest bus departure9:40pm

Panama City to San Jose Bus

Busbud helps you find a bus from Panama City to San Jose. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Panama City to San Jose from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses traveling from Panama City to San Jose, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip Panama City, US - San Jose, US

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
10/16
No data
10/17
$338
Today
$422
10/19
No data
10/20
No data
10/21
No data
10/22
No data
10/23
No data
busbud logoThe cheapest trip from Panama City, US to San Jose, US was searched and found on Oct 17, 2025 with a price of $338

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Panama City, US to San Jose, US, as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Panama City and San Jose!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Panama City to San Jose, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Panama City to San Jose that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Panama City to San Jose.

Did you know?

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Will you be returning to Panama City, US by bus?

Bus from San Jose, US to Panama City, US

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

‌

Popular Buses Connecting Panama City

Buses Leaving from Panama City

Buses Going to Panama City

Popular Buses Connecting San Jose

Buses Leaving from San Jose

Buses Going to San Jose