Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | 199 Spring Garden St. | San Ysidro Bus terminal | CheapestFastest | ||||
| Bus | 199 Spring Garden St. | San Ysidro Bus terminal | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Philadelphia, 199 Spring Garden St | San Ysidro Bus terminal | No tags | ||||
| Bus | 199 Spring Garden St. | San Ysidro Bus terminal | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Philadelphia, 199 Spring Garden St | San Ysidro Bus terminal | No tags |
Last refresh of the prices: Last Saturday at 5:38 PM EST.
Get from Philadelphia to San Ysidro
The journey takes about 3 days, 1 hour 20 minutes, and with fares starting at just $319, it presents an excellent value for a comfortable ride.
Where are the popular stops in Philadelphia and San Ysidro?
Stops in Philadelphia
- BOff of Race Street between 5th Street and, N 6th St, Philadelphia, PA 19106, USA
- C
#2842 St.Vincent St
15th St Trolley Station, Philadelphia, PA 19102, USA - D
Bus Station
1001 Filbert St, Philadelphia, PA 19107, USA - E
Island Av & Suffolk Av MBFS
3000 Island Ave, Philadelphia, PA 19153, USA - F
NRG SEPTA Station
3701 Broad St, Philadelphia, PA 19148, USA
Compare bus companies
Based on 87502 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $319
Frequently asked questions about travelling from Philadelphia, PA to San Ysidro, CA by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Philadelphia to San Ysidro?
The cheapest bus tickets from Philadelphia to San Ysidro start from $319. The average price for this route is around $360. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Philadelphia to San Ysidro?
The average bus travel time from Philadelphia to San Ysidro is 3d 1h, covering a distance of 3810 km. The quickest bus can get you there in 2d 17h and is operated by Greyhound.
Which bus companies service the Philadelphia to San Ysidro route?
Several major bus companies operate on this route with 16 buses available per day.
What are the earliest and latest departure times for the bus from Philadelphia to San Ysidro?
The earliest bus departs from Philadelphia to San Ysidro at 1:50am. And the latest bus departs at 10:00pm.
What are the CO₂ emissions for the bus trip from Philadelphia to San Ysidro?
A bus trip from Philadelphia to San Ysidro generates an estimated 95 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Philadelphia, PA to San Ysidro, CA was searched and found on Jan 17, 2026 with a price of $309To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Philadelphia, PA to San Ysidro, CA, as early as possible.
You can expect to pay from $309 to $376 for a bus ticket from Philadelphia, PA to San Ysidro, CA based on the last 2 days. You can expect to find the cheapest price for the trip at $309 which is on 2026-01-17.
