Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | 199 Spring Garden St. | San Ysidro Bus terminal | CheapestFastest | ||||
| Bus | 199 Spring Garden St. | San Ysidro Bus terminal | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Philadelphia, 199 Spring Garden St | San Ysidro Bus terminal | No tags | ||||
| Bus | 199 Spring Garden St. | San Ysidro Bus terminal | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Philadelphia, 199 Spring Garden St | San Ysidro Bus terminal | No tags |
Last refresh of the prices: Last Saturday at 5:38 PM EST.
Get from Philadelphia to San Ysidro
The journey takes about 3 days, 1 hour 20 minutes and with fares starting at just $224, it presents an excellent value for a comfortable ride.
Where are the popular stops in Philadelphia and San Ysidro?
Stops in Philadelphia
- BOff of Race Street between 5th Street and, N 6th St, Philadelphia, PA 19106, USA
- C
#2842 St.Vincent St
15th St Trolley Station, Philadelphia, PA 19102, USA - D
Bus Station
1001 Filbert St, Philadelphia, PA 19107, USA - E
Island Av & Suffolk Av MBFS
3000 Island Ave, Philadelphia, PA 19153, USA - F
NRG SEPTA Station
3701 Broad St, Philadelphia, PA 19148, USA
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Philadelphia, PA to San Ysidro, CA by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Philadelphia to San Ysidro?
The cheapest bus tickets from Philadelphia to San Ysidro start from $224. The average price for this route is around $253. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Philadelphia to San Ysidro?
The average bus trip duration from Philadelphia to San Ysidro is 3d 1h, covering a distance of 2362 miles (3810 km). The quickest bus can get you there in 2d 17h and is operated by Greyhound.
Which bus companies service the Philadelphia to San Ysidro route?
Several major train operators operate on this route with 16 trains available per day.
What is the earliest and latest departure time for the bus from Philadelphia to San Ysidro?
The earliest bus departs from Philadelphia to San Ysidro at 1:50am. And the latest bus departs at 10:00pm.
What are the CO₂ emissions for the bus trip from Philadelphia to San Ysidro?
A bus trip from Philadelphia to San Ysidro generates an estimated 95 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Philadelphia, PA to San Ysidro, CA was searched and found on Jan 17, 2026 with a price of $217To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Philadelphia, PA to San Ysidro, CA, as early as possible.
You can expect to pay from $217 to $264 for a bus ticket from Philadelphia, PA to San Ysidro, CA based on the last 2 days. You can expect to find the cheapest price for the trip at $217 which is on 2026-01-17.
Top traveled bus routes
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