Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus
| Pittsburgh Intermodal Station | Gateway Station | CheapestFastest |
Last refresh of the prices: Yesterday at 1:55 PM EDT.
Compare 2 ways to go from Pittsburgh to St. Louis
Among the sustainable travel choices, the Bus stands out as a good way to reach St. Louis. The journey takes about 13 hours 55 minutes, and with fares starting at just CLP 57,756, it presents an excellent value for a comfortable ride.
Bus stations and stops in Pittsburgh and St. Louis
Stops in Pittsburgh
- A
Intermodal Station
55 11th St, Pittsburgh, PA 15222, USA - B
Sennott Square
201 S Bouquet St, Pittsburgh, PA 15213, USA
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Frequently asked questions about travelling from Pittsburgh to St. Louis by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Pittsburgh to St. Louis?
The cheapest bus tickets from Pittsburgh to St. Louis start from CLP 57,756. The average price for this route is around CLP 77,617. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Pittsburgh to St. Louis?
The average bus travel time from Pittsburgh to St. Louis is 13h 55m, covering a distance of 899 km. The quickest bus can get you there in 12h 30m and is operated by Greyhound.
Which bus companies service the Pittsburgh to St. Louis route?
What are the earliest and latest departure times for the bus from Pittsburgh to St. Louis?
The earliest bus departs from Pittsburgh to St. Louis at 1:25am. And the latest bus departs at 8:15pm.
What are the CO₂ emissions for the bus trip from Pittsburgh to St. Louis?
A bus trip from Pittsburgh to St. Louis generates an estimated 22.454525 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Pittsburgh to St. Louis?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 88149 reviews.
Which bus company has the best Wi-Fi from Pittsburgh to St. Louis?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from Pittsburgh to St. Louis?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Pittsburgh to St. Louis?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Pittsburgh to St. Louis was searched and found on Sep 29, 2026 with a price of CLP 50,636To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Pittsburgh to St. Louis, as early as possible.
You can expect to pay from CLP 50,636 to CLP 149,940 for a bus ticket from Pittsburgh to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at CLP 50,636 which is on 2026-09-29.
What's the cheapest way to go from Pittsburgh to St. Louis?
The Bus is the cheapest travel choice for this destination
