What is the travel distance from Rochester to San Diego?

It's about 3623 km (2246 miles) from Rochester to San Diego.

What are the departure and arrival locations for buses traveling from Rochester to San Diego?

Buses departing from Bus Station in Rochester will take you to Mission Valley Sheraton in San Diego.

Bus Rochester to San Diego from $325 | Refundable Tickets

Previously seen trips

Next departures for Rochester to San Diego on November 24
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound + FlixBus	Bus	6:55pm	Rochester	3d 1h	5:35pm	UCSD Health La Jolla Station	No tags
Greyhound + FlixBus	Bus	6:55pm	Rochester	3d 5h	9:30pm	Downtown SD (Seaport)	No tags
	Bus	6:55pm	Rochester	3d 1h	5:45pm	Greyhound Bus Stop	No tags
FlixBus + Greyhound	Bus	10:15pm	Rochester	3d 18h	1:35pm	5716 Hardy Ave	No tags
Greyhound + FlixBus	Bus	10:15pm	Rochester	3d 14h	10:10am	Balboa Park	No tags

Compare 2 ways to go from Rochester to San Diego

We recommend taking the train

Among the sustainable travel choices, the train stands out as a good way to reach San Diego. The journey takes about 2 days, 16 hours 24 minutes, and with fares starting at just $468, it presents an excellent value for a comfortable ride.

2train per day

2d 16hAverage Duration

3621 kmDistance

329kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$325 - $890	Average Duration3d 11h	CO₂ emissions 91kg CO₂e
Train	Average Price$468 - $3,050	Average Duration2d 16h	CO₂ emissions 329kg CO₂e

Where are the popular stops in Rochester and San Diego?

Stops in Rochester

A
Bus Station
186 Cumberland St (Across from the Amtrak Terminal) , Rochester, NY 14605
Visit page
B
U of R
Rush Rhees Library, 755 Library Road, Rochester, NY 14627
Visit page
C
Rochester Institute of Technology
61 Lomb Memorial Dr, Rochester, NY 14623
Visit page

Stops in San Diego

A
Mission Valley Sheraton
1433 Camino del Rio S, San Diego, CA 92108, USA
B
Old Town Courtyard Marriot
2435 Jefferson St, San Diego, CA 92110, USA
C
Downtown Holiday Inn
1617 1st Ave, San Diego, CA 92101, USA
D
Greyhound Station
1313 National Ave, San Diego, CA 92101, USA
E
Market St. & Park Blvd
601 Park Boulevard, San Diego, CA 92101, USA
F
San Ysidro McDonald's
727 E San Ysidro Blvd, San Diego, CA 92173, USA

Compare bus companies

Greyhound

3.5/587,393 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

FlixBus

3.5/511,425 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

US Bus Companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about travelling from Rochester, NY, US to San Diego, CA, US by bus

What is the travel distance from Rochester to San Diego?
It's about 3623 km (2246 miles) from Rochester to San Diego.
What are the departure and arrival locations for buses traveling from Rochester to San Diego?
Buses departing from Bus Station in Rochester will take you to Mission Valley Sheraton in San Diego.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11-22

No data

11-23

$771

Today

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11-25

No data

11-26

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11-27

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11-28

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11-29

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The cheapest trip from Rochester, NY, US to San Diego, CA, US was searched and found on Nov 23, 2025 with a price of $771

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Rochester, NY, US to San Diego, CA, US, as early as possible.