Bus Tickets from Rome to Isernia

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TodayMay 4
from US$23
TomorrowMay 5
from US$13
TueMay 6
from US$17
WedMay 7
ThuMay 8
from US$31
FriMay 9
from US$12
SatMay 10
from US$13
SunMay 11

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: May 5 at
    Departure city: Rome
    Departure location: Rome Tiburtina Bus Station
    Arrival time: May 5 at
    Destination city: Isernia
    Destination location: Isernia
    Operated by: Flixbus Flixbus
    Vehicle: BusDuration:
  • Departure time: May 5 at
    Departure city: Rome
    Departure location: Rome Fiumicino Airport
    Arrival time: May 5 at
    Destination city: Isernia
    Destination location: Isernia
    Operated by: Flixbus Flixbus
    Vehicle: BusDuration:
  • Departure time: May 5 at
    Departure city: Rome
    Departure location: Rome Fiumicino Airport
    Arrival time: May 5 at
    Destination city: Isernia
    Destination location: Isernia
    Operated by: Flixbus Flixbus
    Vehicle: BusDuration:
  • Departure time: May 5 at
    Departure city: Rome
    Departure location: Aeroporto Ciampino Airport (CIA)
    Arrival time: May 5 at
    Destination city: Isernia
    Destination location: Isernia
    Operated by: Flixbus Flixbus
    Vehicle: BusDuration:

Last refresh of the prices: Yesterday at 11:40 PM CEST.

Prices and availability are subject to change.

Accepted payments

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Compare 3 ways to go from Rome to Isernia

Bus
Average PriceUS$11 - US$78Average Duration6h 44m
3kg CO₂e5 out of 5 stars
Most eco-friendly
Train
Average PriceUS$20 - US$30Average Duration2h 12m
4kg CO₂e5 out of 5 stars
Carpool
Average PriceUS$11 - US$27Average Duration2h
6kg CO₂e4 out of 5 stars
CheapestFastest
busbud logoBusbud recommends carpooling from Rome to Isernia

Among the sustainable travel choices, the carpool stands out as a good way to reach Isernia. The journey takes about 2 hours, and with fares starting at just US$11, it presents an excellent value for a comfortable ride.

3carpool per day
2hAverage Duration
US$11Cheapest ticket
6kgCO₂ emissions

Bus Rome to Isernia: Trip Overview

Average Ticket PriceUS$31
Average Bus Trip Duration6h 44m
Number of daily buses3
Earliest bus departure4:05am
Distance138 km
Latest bus departure1:00pm

Rome to Isernia Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Rome to Isernia.

Bus service from Rome to Isernia will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses travelling from Rome to Isernia, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Rome - Isernia

  1. How long does it take to get to Isernia from Rome by bus?

    The typical travel time from Rome to Isernia by bus is around 6h 44m. For the shortest travel time, select the fastest bus available, which will take you to Isernia in about 2h 35m.

  2. What is the distance between Rome and Isernia?

    The distance between Rome and Isernia is around 150 km (93 miles).

  3. What are the departure and arrival locations for buses traveling from Rome to Isernia?

    Buses traveling this route start their trip at Rome Tiburtina Bus Station, in Rome, and end it at Isernia, in Isernia.

  4. What is the cheapest way to go from Rome to Isernia?

    The least expensive option to go from Rome to Isernia would be going by bus. Starting at US$11, this bus is the most cost-effective option for your journey.

  5. How much is the bus from Rome to Isernia?

    The bus fare from Rome to Isernia is approximately US$31.

  6. Can you take a day trip from Rome to Isernia?

    Yes! Taking a day trip from Rome to Isernia is very much possible. You'll spend about 5h 10m on the round-trip journey between Rome and Isernia. Before booking, make sure to check the departure and arrival times to ensure you'll have enough time to explore Isernia.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05-02
US$34
05-03
US$35
Today
US$21
05-05
US$11
05-06
US$14
05-07
US$14
05-08
US$28
05-09
US$10
busbud logoThe cheapest trip from Rome to Isernia was searched and found on May 9, 2025 with a price of US$10

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Rome to Isernia, as early as possible.

You can expect to pay from US$10 to US$53 for a bus ticket from Rome to Isernia based on the last 2 days. You can expect to find the cheapest price for the trip at US$10 which is on 2025-05-09.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Rome to Isernia but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from Rome to Isernia, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Rome to Isernia that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from Rome to Isernia while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Will you be returning to Rome by bus?

Bus from Rome to Isernia

You can also go to Isernia by train

Train from Rome to Isernia

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