How much is the bus ticket from San Antonio to St. Louis?

The cheapest bus tickets from San Antonio to St. Louis start from $143. The average price for this route is around $217. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from San Antonio to St. Louis?

The average bus travel time from San Antonio to St. Louis is 23h 40m, covering a distance of 1275 km. The quickest bus can get you there in 1d and is operated by Greyhound .

Which bus companies service the San Antonio to St. Louis route?

Several major bus companies operate on this route with 6 buses available per day, including services from Greyhound , Valley Transit .

What are the earliest and latest departure times for the bus from San Antonio to St. Louis?

The earliest bus departs from San Antonio to St. Louis at 1:30am. And the latest bus departs at 9:15pm.

What are the CO₂ emissions for the bus trip from San Antonio to St. Louis?

A bus trip from San Antonio to St. Louis generates an estimated 32 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.

What is the best bus company from San Antonio to St. Louis?

According to Busbud customers, the highest-rated bus company on this route is Greyhound , with an average rating of 3.5 out of 5 stars based on 87500 reviews.

Which bus company has the best Wi-Fi from San Antonio to St. Louis?

Based on Busbud reviews, the bus company Valley Transit has the highest Wi-Fi rating with a score of 2.8.

Which bus company has the best on-time performance from San Antonio to St. Louis?

According to Busbud traveller reviews, the most punctual bus company on this route is Valley Transit , with a punctuality rating of 3.4 out of 5 stars.

Which bus company has the cleanest buses from San Antonio to St. Louis?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Greyhound , with a cleanliness rating of 3.3 out of 5 stars.

Bus San Antonio to St. Louis from $144 | Refundable Tickets

Next bus departures

Next departures for San Antonio to St. Louis on January 26
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
Greyhound Lines Mexico + Greyhound Lines, Inc.	Bus	7:15pm	San Antonio Bus Station	1d 3h	10:15pm	Saint Louis (Lambert Field)	CheapestFastest
Greyhound Lines Mexico + Greyhound Lines, Inc.	Bus	7:15pm	San Antonio Bus Station	1d 3h	10:45pm	Gateway Station	No tags

Next departures for San Antonio to St. Louis on January 27
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	12:35pm	San Antonio Bus Station	1d	12:55pm	Gateway Station	Cheapest
Greyhound Lines Mexico + Greyhound Lines, Inc.	Bus	1:30am	San Antonio Bus Station	20h 45m	10:15pm	Saint Louis (Lambert Field)	Fastest
Greyhound Lines Mexico + Greyhound Lines, Inc.	Bus	1:30am	San Antonio Bus Station	21h 15m	10:45pm	Gateway Station	No tags
Greyhound Lines Mexico + Greyhound Lines, Inc.	Bus	7:15pm	San Antonio Bus Station	1d 3h	10:45pm	Gateway Station	No tags
Greyhound Lines Mexico + Greyhound Lines, Inc.	Bus	7:15pm	San Antonio Bus Station	1d 3h	10:15pm	Saint Louis (Lambert Field)	No tags

Next departures for San Antonio to St. Louis on January 28
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Valley Transit + Greyhound Lines, Inc.	Bus	9:15pm	San Antonio Bus Station	1d 1h	10:15pm	Saint Louis (Lambert Field)	Cheapest
Greyhound Lines Mexico + Greyhound Lines, Inc.	Bus	1:30am	San Antonio Bus Station	20h 45m	10:15pm	Saint Louis (Lambert Field)	Fastest
Greyhound Lines Mexico + Greyhound Lines, Inc.	Bus	1:30am	San Antonio Bus Station	21h 15m	10:45pm	Gateway Station	No tags
Valley Transit + Greyhound Lines, Inc.	Bus	9:15pm	San Antonio Bus Station	1d 1h	10:45pm	Gateway Station	No tags
	Bus	12:35pm	San Antonio Bus Station	1d	12:55pm	Gateway Station	No tags

Next departures for San Antonio to St. Louis on January 29
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines Mexico + Greyhound Lines, Inc.	Bus	1:30am	San Antonio Bus Station	21h 15m	10:45pm	Gateway Station	Cheapest
Greyhound Lines Mexico + Greyhound Lines, Inc.	Bus	1:30am	San Antonio Bus Station	20h 45m	10:15pm	Saint Louis (Lambert Field)	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	7:30am	San Antonio Bus Station	23h 40m	7:10am	Gateway Station	No tags
	Bus	12:35pm	San Antonio Bus Station	1d	12:55pm	Gateway Station	No tags
Valley Transit + Greyhound Lines, Inc.	Bus	9:15pm	San Antonio Bus Station	1d 1h	10:45pm	Gateway Station	No tags

Next departures for San Antonio to St. Louis on January 30
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Valley Transit + Greyhound Lines, Inc.	Bus	9:15pm	San Antonio Bus Station	1d 1h	10:45pm	Gateway Station	Cheapest
Greyhound Lines Mexico + Greyhound Lines, Inc.	Bus	1:30am	San Antonio Bus Station	20h 45m	10:15pm	Saint Louis (Lambert Field)	Fastest
Greyhound Lines Mexico + Greyhound Lines, Inc.	Bus	1:30am	San Antonio Bus Station	21h 15m	10:45pm	Gateway Station	No tags
FlixBus + Greyhound Lines, Inc.	Bus	7:30am	San Antonio Bus Station	23h 40m	7:10am	Gateway Station	No tags
Valley Transit + Greyhound Lines, Inc.	Bus	9:15pm	San Antonio Bus Station	1d 1h	10:15pm	Saint Louis (Lambert Field)	No tags

Next departures for San Antonio to St. Louis on January 31
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	7:30am	San Antonio Bus Station	23h 40m	7:10am	Gateway Station	Cheapest
Greyhound Lines Mexico + Greyhound Lines, Inc.	Bus	1:30am	San Antonio Bus Station	20h 45m	10:15pm	Saint Louis (Lambert Field)	Fastest
Greyhound Lines Mexico + Greyhound Lines, Inc.	Bus	1:30am	San Antonio Bus Station	21h 15m	10:45pm	Gateway Station	No tags
Valley Transit + Greyhound Lines, Inc.	Bus	9:15pm	San Antonio Bus Station	1d 1h	10:45pm	Gateway Station	No tags
FlixBus + Greyhound Lines, Inc.	Bus	7:45am	Pearl District	23h 25m	7:10am	Gateway Station	No tags

Last refresh of the prices: Last Friday at 2:41 PM CST.

Compare 2 ways to go from San Antonio to St. Louis

We recommend taking the bus

Among the sustainable travel choices, the Bus stands out as a good way to reach St. Louis. The journey takes about 23 hours 40 minutes, and with fares starting at just $143, it presents an excellent value for a comfortable ride.

6bus per day

23h 40mAverage Duration

1275 kmDistance

32kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$143 - $559	Average Duration23h 40m	CO₂ emissions 32kg CO₂e
Train	Average Price$158 - $1,031	Average Duration1d	CO₂ emissions 116kg CO₂e

Where are the popular stops in San Antonio and St. Louis?

Stops in San Antonio

A
San Antonio Bus Station
500 N St Mary's St, San Antonio, TX 78205, USA
Visit page
B
Tornado I-35
7914 Interstate 35 Access Rd, San Antonio, TX 78224, USA
Visit page
C
4407 S PanAm Expy #101
4407 S PanAm Expy #101, San Antonio, TX 78225, USA
Visit page
D
San Antonio, TX
165 Bowie St, San Antonio, 78205
Visit page

Stops in St. Louis

A
Gateway Station
430 S 15th St, St Louis, MO 63103
Visit page

Compare bus companies

Greyhound

3.5/587,517 reviews

Staff3.6

Timeliness2.9

Cleanliness3.4

Wifi2.5

Valley Transit

3/539 reviews

Staff4

Timeliness3.4

Cleanliness3

Wifi2.8

US bus companies:FlixBus, BlaBlaCar Bus, Greyhound, ALSA, Intercape, Trenitalia, Big Sky

Frequently asked questions about travelling from San Antonio, US to St. Louis by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from San Antonio to St. Louis?
The cheapest bus tickets from San Antonio to St. Louis start from $143. The average price for this route is around $217. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from San Antonio to St. Louis?
The average bus travel time from San Antonio to St. Louis is 23h 40m, covering a distance of 1275 km. The quickest bus can get you there in 1d and is operated by Greyhound.
Which bus companies service the San Antonio to St. Louis route?
Several major bus companies operate on this route with 6 buses available per day, including services from Greyhound, Valley Transit.
What are the earliest and latest departure times for the bus from San Antonio to St. Louis?
The earliest bus departs from San Antonio to St. Louis at 1:30am. And the latest bus departs at 9:15pm.
What are the CO₂ emissions for the bus trip from San Antonio to St. Louis?
A bus trip from San Antonio to St. Louis generates an estimated 32 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from San Antonio to St. Louis?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87500 reviews.
Which bus company has the best Wi-Fi from San Antonio to St. Louis?
Based on Busbud reviews, the bus company Valley Transit has the highest Wi-Fi rating with a score of 2.8.
Which bus company has the best on-time performance from San Antonio to St. Louis?
According to Busbud traveller reviews, the most punctual bus company on this route is Valley Transit, with a punctuality rating of 3.4 out of 5 stars.
Which bus company has the cleanest buses from San Antonio to St. Louis?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Greyhound, with a cleanliness rating of 3.3 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

01-24

$271

01-25

$256

Today

$252

01-27

$259

01-28

$235

01-29

$235

01-30

$274

01-31

$274

The cheapest trip from San Antonio, US to St. Louis was searched and found on Jan 28, 2026 with a price of $235

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Antonio, US to St. Louis, as early as possible.

You can expect to pay from $235 to $274 for a bus ticket from San Antonio, US to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $235 which is on 2026-01-28.