Bus Tickets from San Antonio, US to St. Louis

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TodaySep 3
from $106
TomorrowSep 4
FriSep 5
from $106
SatSep 6
SunSep 7
MonSep 8
TueSep 9
from $114
WedSep 10

Cheap buses leaving Friday

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: September 5 at
    Departure city: San Antonio
    Departure location: San Antonio Bus Station
    Arrival time: September 6 at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: Valley Transit + Greyhound Lines, Inc.
    Valley Transit + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: September 5 at
    Departure city: San Antonio
    Departure location: San Antonio Bus Station
    Arrival time: September 5 at
    Destination city: St. Louis
    Destination location: Saint Louis (Lambert Field)
    Operated by: Greyhound Lines Mexico + Greyhound Lines, Inc.
    Greyhound Lines Mexico + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: September 5 at
    Departure city: San Antonio
    Departure location: San Antonio Bus Station
    Arrival time: September 5 at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: Greyhound Lines Mexico + Greyhound Lines, Inc.
    Greyhound Lines Mexico + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: September 5 at
    Departure city: San Antonio
    Departure location: San Antonio Bus Station
    Arrival time: September 6 at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: Greyhound Lines Mexico + FlixBus + Greyhound Lines, Inc.
    Greyhound Lines Mexico + FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: September 5 at
    Departure city: San Antonio
    Departure location: San Antonio Bus Station
    Arrival time: September 6 at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Compare 2 ways to go from San Antonio to St. Louis.

Bus
Average Price$88 - $367Average Duration1d 1h
32kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average Price$112 - $191Average Duration1d
116kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the bus from San Antonio to St. Louis

Among the sustainable travel choices, the bus stands out as the good way to reach St. Louis. The journey takes about 1 day, 1 hour and with fares starting at just $88, it presents an excellent value for a comfortable ride.

7bus per day
1d 1hAverage Duration
$88Cheapest ticket
32kgCO₂ emissions

Bus San Antonio, US to St. Louis: Trip Overview

Average ticket price$114
Average bus trip duration1d 1h
Number of daily buses7
Earliest bus departure1:30am
Distance791 miles (1275 km)
Latest bus departure9:00pm

San Antonio to St. Louis Bus

Busbud helps you find a bus from San Antonio to St. Louis. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make it our job to connect you with the most dependable bus companies that cover bus service from San Antonio to St. Louis.

Discover how much the bus trip from San Antonio to St. Louis will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions for your trip San Antonio, US - St. Louis

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09/01
$133
09/02
No data
Today
$99
09/04
$94
09/05
$129
09/06
$91
09/07
$90
09/08
$103
busbud logoThe cheapest trip from San Antonio, US to St. Louis was searched and found on Sep 7, 2025 with a price of $90

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Antonio, US to St. Louis, as early as possible.

You can expect to pay from $90 to $133 for a bus ticket from San Antonio, US to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $90 which is on 2025-09-07.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between San Antonio and St. Louis!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from San Antonio to St. Louis.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from San Antonio to St. Louis will emit less CO2 than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from San Antonio to St. Louis.

Did you know?

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

What's the cheapest way to go from San Antonio, US to St. Louis?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to San Antonio, US by bus?

Bus from St. Louis to San Antonio, US

You can also go to St. Louis by train

Train from San Antonio, US to St. Louis

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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