- San Diego to Knoxville buses
Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound + FlixBus | UCSD Health La Jolla Station | Knoxville Bus Station | No tags | |||||
Greyhound + FlixBus | San Diego (Old Town-FlixBus) | Knoxville Bus Station | No tags | |||||
FlixBus + Greyhound | UCSD Health La Jolla Station | Knoxville Bus Station | No tags | |||||
Greyhound + FlixBus | UCSD Health La Jolla Station | Knoxville Bus Station | No tags | |||||
![]() | Greyhound Bus Stop | Knoxville Bus Station | No tags |
Accepted payments
Get from San Diego to Knoxville
The journey takes about 2 days, 7 hours 50 minutes, and with fares starting at just US$579, it presents an excellent value for a comfortable ride.
Bus San Diego, CA, US to Knoxville, TN: Trip Overview
Compare bus companies
San Diego to Knoxville Bus
With Busbud, comparing and booking tickets for a bus from San Diego to Knoxville is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
Bus service from San Diego to Knoxville will be provided by the most trusted bus companies.
Discover how much the bus trip from San Diego to Knoxville will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.
Where are the popular stops in San Diego and Knoxville?
Frequently asked questions on the trip San Diego, CA, US - Knoxville, TN
What is the travel distance from San Diego to Knoxville?
The distance covered from San Diego to Knoxville is 3062 km (1899 miles).
What are the departure and arrival locations for buses traveling from San Diego to Knoxville?
Buses traveling this route start their trip at Mission Valley Sheraton, in San Diego, and end it at 100 Kirkwood St, in Knoxville.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while travelling from San Diego to Knoxville.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
Much more than a mere vehicle taking you from San Diego to Knoxville, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.
Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from San Diego to Knoxville will emit less CO2 than a car or an airplane.
Tune out to the fine sounds of your best music playlist on your bus trip from San Diego to Knoxville while indulging in miles on end of beautiful scenic views.
Did you know?
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.
Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.
Top travelled bus routes
Why choose Busbud?
The Best Way To Book Bus and Train Tickets
Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.
People from around the world trust Busbud
Popular Buses Connecting San Diego
Buses Leaving from San Diego
- Bus from San Diego to San Ysidro
- Bus San Diego - Lafayette
- San Diego - Lafayette
- Bus from San Diego to San Marcos
- Bus San Diego - San Francisco
- San Diego - Las Vegas
- Bus from San Diego to Los Angeles
- Bus San Diego - Palm Springs
- San Diego - Phoenix
- Bus from San Diego to Las Vegas
- Bus San Diego - Wilmington
- San Diego - Temecula
- Bus from San Diego to Anaheim
- Bus San Diego - Medford
- San Diego - Yuma
Buses Going to San Diego
- Bus from Manchester to San Diego
- Bus San Marcos - San Diego
- Santa Fe - San Diego
- Bus from Grants to San Diego
- Bus Chicago - San Diego
- Seattle - San Diego
- Bus from Palm Springs to San Diego
- Bus Yuma - San Diego
- Las Vegas - San Diego
- Bus from Anaheim to San Diego
- Bus Bellingham - San Diego
- Willcox - San Diego
- Bus from Effingham to San Diego
- Bus Phoenix - San Diego
- Meridian - San Diego
Popular Buses Connecting Knoxville
Buses Leaving from Knoxville
- Bus from Knoxville to Charlotte
- Bus Knoxville - Marathon
- Knoxville - Lexington
- Bus from Knoxville to Chicago
- Bus Knoxville - Orlando
- Knoxville - Greenville
- Bus from Knoxville to Toledo
- Bus Knoxville - New York City
- Knoxville - Nashville
- Bus from Knoxville to Baltimore
- Bus Knoxville - Myrtle Beach
- Knoxville - Scranton
- Bus from Knoxville to Jackson
- Bus Knoxville - Columbus
- Knoxville - Fort Lauderdale
Buses Going to Knoxville
- Bus from Nashville to Knoxville
- Bus Memphis - Knoxville
- Charlotte - Knoxville
- Bus from Chicago to Knoxville
- Bus Tampa - Knoxville
- Detroit - Knoxville
- Bus from Fredericksburg to Knoxville
- Bus New York City - Knoxville
- Boston - Knoxville
- Bus from San Diego to Knoxville
- Bus Orlando - Knoxville
- Indianapolis - Knoxville
- Bus from Murfreesboro to Knoxville
- Bus El Paso - Knoxville
- Pittsburgh - Knoxville
Popular routes in this country
- Bus from Washington to New York City
- Bus Boston - New York City
- New York City - Boston
- Bus from Philadelphia to New York City
- Bus Niagara Falls - New York City
- Buffalo - New York City
- Bus from Baton Rouge to New Orleans
- Bus Baltimore - New York City
- Atlanta - Savannah
- Bus from Albany to New York City
- Bus New York City - Burlington
- Las Vegas - Los Angeles
- Bus from Detroit to Chicago
- Bus Los Angeles - San Diego
- Miami - Orlando







