Bus Tickets from San Diego, CA, US to Mesa

Previously seen trips

Next departures for San Diego to Mesa on November 21
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound + FlixBus
Bus
UCSD Health La Jolla Station
Mesa Bus StopNo tags
FlixBus + Greyhound
Bus
San Diego (Old Town-FlixBus)
Mesa Bus StopNo tags
FlixBus + Greyhound
Bus
UCSD Health La Jolla Station
Mesa Bus StopNo tags
GreyhoundBus
Greyhound Bus Stop
Mesa Bus StopNo tags
GreyhoundBus
Greyhound Bus Stop
Mesa Bus StopNo tags

Get from San Diego to Mesa

This route is served by bus only

The journey takes about 12 hours 35 minutes, and with fares starting at just $82, it presents an excellent value for a comfortable ride.

8bus per day
12h 35mAverage Duration
503 kmDistance
13kgCO₂ emissions

Frequently asked questions about travelling from San Diego, CA, US to Mesa by bus

  1. What is the distance between San Diego and Mesa?

    The distance between San Diego and Mesa is around 502 km (312 miles).

  2. What are the departure and arrival locations for buses traveling from San Diego to Mesa?

    Buses traveling this route start their trip at Mission Valley Sheraton, in San Diego, and end it at Mesa Bus Station, in Mesa.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11-19
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11-20
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Today
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11-22
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11-23
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11-24
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11-25
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11-26
$110
busbud logoThe cheapest trip from San Diego, CA, US to Mesa was searched and found on Nov 26, 2025 with a price of $110

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Diego, CA, US to Mesa, as early as possible.

You can expect to pay from $110 to $110 for a bus ticket from San Diego, CA, US to Mesa based on the last 2 days. You can expect to find the cheapest price for the trip at $110 which is on 2025-11-26.

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