Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound | Bus | Santa Ana Bus Station | 151 Steel Pl, Cambridge | No tags | ||||
FlixBus + Greyhound | Bus | Santa Ana Bus Station | Brookline | No tags | ||||
Greyhound + FlixBus | Bus | Anaheim Regional Transportation Intermodal Center | Brookline | No tags | ||||
 | Bus | Anaheim Regional Transportation Intermodal Center | Boston (South Station) | No tags | ||||
Greyhound + FlixBus | Bus | Anaheim Regional Transportation Intermodal Center | 151 Steel Pl, Cambridge | No tags |
Get from Santa Ana to Boston
The journey takes about 3 days, 5 hours 20 minutes, and with fares starting at just $315, it presents an excellent value for a comfortable ride.
Where are the popular stops in Santa Ana and Boston?
Stops in Santa Ana
- A
Santa Ana Greyhound Bus Station
1000 E Santa Ana Blvd, Santa Ana, CA 92701 - B
602 S Main St
602 S Main St, Santa Ana, CA 92701, USA
Stops in Boston
- A145 Dartmouth St, Boston, MA 02116, USA
- B100 Legends Way, Boston, MA 02114, USA
- C335 Grove St, Auburndale, MA 02466
- D
Prudential MBTA Station
220 Huntington Ave, Boston, MA 02115, USA - E
Copley MBTA Station
650 Boylston St, Boston, MA 02116, USA - F
Long Wharf
66 Long Wharf, Boston, MA 02110, USA
Compare bus companies
Based on 87518 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi‑Fi. Greyhound ticket prices on this trip start at $317
Frequently asked questions about travelling from Santa Ana, US to Boston, MA, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Santa Ana to Boston?
The cheapest bus tickets from Santa Ana to Boston start from $315. The average price for this route is around $347. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Santa Ana to Boston?
The average bus travel time from Santa Ana to Boston is 3d 5h, covering a distance of 4148 km. The quickest bus can get you there in 3d 4h and is operated by Greyhound.
Which bus companies service the Santa Ana to Boston route?
Several major bus companies operate on this route with 9 buses available per day.
What are the earliest and latest departure times for the bus from Santa Ana to Boston?
The earliest bus departs from Santa Ana to Boston at 7:55am. And the latest bus departs at 9:40pm.
What are the CO₂ emissions for the bus trip from Santa Ana to Boston?
A bus trip from Santa Ana to Boston generates an estimated 104 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Santa Ana, US to Boston, MA, US was searched and found on Jan 27, 2026 with a price of $337To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santa Ana, US to Boston, MA, US, as early as possible.
