What is the distance between Santa Fe and Colón?

Santa Fe and Colón are 251 km (156 miles) apart.

What are the departure and arrival locations for buses traveling from Santa Fe to Colón?

Buses departing from Estación Terminal de Ómnibius, Santa Fe in Santa Fe will take you to Terminal de Omnibus Colón in Colón.

Bus Santa Fe to Colón from $34 | Refundable Tickets

Previously seen trips

Next departures for Santa Fe to Colón on November 22
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	12:15pm	Estación Terminal de Ómnibius, Santa Fe	4h 45m	5:00pm	Terminal de Omnibus Colón	No tags
Bus	12:15pm	Estación Terminal de Ómnibius, Santa Fe	4h 50m	5:05pm	Colón Acceso	No tags
Bus	3:20pm	Estación Terminal de Ómnibius, Santa Fe	4h 45m	8:05pm	Terminal de Omnibus Colón	No tags
Bus	6:15pm	Estación Terminal de Ómnibius, Santa Fe	4h 50m	11:05pm	Colón Acceso	No tags
Bus	6:15pm	Estación Terminal de Ómnibius, Santa Fe	4h 45m	11:00pm	Terminal de Omnibus Colón	No tags

Get from Santa Fe to Colón

This route is served by bus only

The journey takes about 4 hours 45 minutes, and with fares starting at just $37, it presents an excellent value for a comfortable ride.

6bus per day

4h 45mAverage Duration

250 kmDistance

6kgCO₂ emissions

Where are the popular stops in Santa Fe and Colón?

Stops in Santa Fe

A
Estación Terminal de Ómnibius, Santa Fe
Estación Terminal de Onmibus Belgrano 2900 , S3000GCH Santa Fe, Argentina
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Stops in Colón

A
Terminal de Omnibus Colón
Sourigues 449, Colón, Entre Ríos, Argentina
Visit page
B
Colón Acceso
RN14, Entre Ríos, Argentina
Visit page

Compare bus companies

Flechabus

4/52,116 reviews

Staff4.7

Timeliness3.4

Cleanliness4.1

Wifi1.9

Based on 2116 reviews, the company was rated 3.8 stars on Busbud. Travellers were especially satisfied with the ticket access and the staff but often complained with the WiFi. Flechabus ticket prices on this trip start at $37

Flecha bus Santa Fe Colón recent customer reviews

All as expected but the temperature was too cold and the fan was not controllable. Therefore we froze.

Margaret C.

February 13, 2018

Encon

4/5132 reviews

Staff4.7

Timeliness3.1

Cleanliness4.4

Wifi2.3

Nuevo Expreso

4/5299 reviews

Staff4.5

Timeliness3.3

Cleanliness4.1

Wifi1.9

Río Uruguay

Rio Uruguay

4/5571 reviews

Staff4.5

Timeliness3.7

Cleanliness4

Wifi0.4

AR Bus Companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about travelling from Santa Fe, AR to Colón, Entre Rios, AR by bus

What is the distance between Santa Fe and Colón?
Santa Fe and Colón are 251 km (156 miles) apart.
What are the departure and arrival locations for buses traveling from Santa Fe to Colón?
Buses departing from Estación Terminal de Ómnibius, Santa Fe in Santa Fe will take you to Terminal de Omnibus Colón in Colón.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11-20

$34

11-21

$31

Today

$34

11-23

$34

11-24

$34

11-25

$34

11-26

$34

11-27

$34

The cheapest trip from Santa Fe, AR to Colón, Entre Rios, AR was searched and found on Nov 21, 2025 with a price of $31

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santa Fe, AR to Colón, Entre Rios, AR, as early as possible.

You can expect to pay from $31 to $38 for a bus ticket from Santa Fe, AR to Colón, Entre Rios, AR based on the last 2 days. You can expect to find the cheapest price for the trip at $34 which is on 2025-11-23.

Usually Flechabus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.