Bus Tickets from Santa Fe to Santiago del Estero

Find affordable bus tickets from Santa Fe to Santiago del Estero with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.

Bus Santa Fe to Santiago del Estero: Trip Overview

Average Ticket PriceUS$53
Average Bus Trip Duration9h 20m
Number of daily buses1
Earliest bus departure7:50pm
Distance550 km
Latest bus departure8:10pm

Santa Fe to Santiago del Estero Bus

With Busbud, comparing and booking tickets for a bus from Santa Fe to Santiago del Estero is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from Santa Fe to Santiago del Estero will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses travelling from Santa Fe to Santiago del Estero, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Santa Fe - Santiago del Estero

  1. How long is the bus trip from Santa Fe to Santiago del Estero?

    The typical travel time from Santa Fe to Santiago del Estero by bus is around 9h 20m. The fastest bus on this trip will get to Santiago del Estero in 9h 20m

  2. How far is Santa Fe from Santiago del Estero?

    The distance covered from Santa Fe to Santiago del Estero is 549 km (341 miles).

  3. What are the departure and arrival locations for buses traveling from Santa Fe to Santiago del Estero?

    Buses traveling this route start their trip at Estación Terminal de Ómnibius, Santa Fe, in Santa Fe, and end it at Terminal de Ómnibus de Santiago del Estero, in Santiago del Estero.

  4. What is the cheapest way to go from Santa Fe to Santiago del Estero?

    The least expensive option to go from Santa Fe to Santiago del Estero would be going by bus. With a starting ticket price of US$37, this bus becomes your top pick for this journey.

  5. How much does it cost to take the bus from Santa Fe to Santiago del Estero?

    The bus fare from Santa Fe to Santiago del Estero is approximately US$53.

  6. Can I take an overnight bus from Santa Fe to Santiago del Estero?

    Yes! Catch buses leaving from Santa Fe until 8:10pm and reaching Santiago del Estero on the following day.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05-07
No data
05-08
No data
Today
US$48
05-10
No data
05-11
No data
05-12
No data
05-13
No data
05-14
US$52
busbud logoThe cheapest trip from Santa Fe to Santiago del Estero was searched and found on May 9, 2025 with a price of US$48

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santa Fe to Santiago del Estero, as early as possible.

You can expect to pay from US$48 to US$58 for a bus ticket from Santa Fe to Santiago del Estero based on the last 2 days. You can expect to find the cheapest price for the trip at US$52 which is on 2025-05-14.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Santa Fe to Santiago del Estero.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from Santa Fe to Santiago del Estero, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Santa Fe to Santiago del Estero that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from Santa Fe to Santiago del Estero, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Will you be returning to Santa Fe by bus?

Bus from Santa Fe to Santiago del Estero

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. Use Busbud to book your trip online, in your own language and currency, wherever you are. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

‌

Popular Buses Connecting Santa Fe

Buses Leaving from Santa Fe

Buses Going to Santa Fe

Popular Buses Connecting Santiago del Estero

Buses Leaving from Santiago del Estero

Buses Going to Santiago del Estero