Find coaches from Santa Fe, AR to Santiago del Estero

Find affordable coach tickets from Santa Fe, AR to Santiago del Estero with flexible options. Book your journey now

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Today30 Jun
from US$36
Tomorrow1 Jul
Wed2 Jul
Thu3 Jul
Fri4 Jul
Sat5 Jul
Sun6 Jul
Mon7 Jul

Cheap buses leaving today

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 30 June at
    Departure city: Santa Fe
    Departure location: Estación Terminal de Ómnibius, Santa Fe
    Arrival time: 1 July at
    Destination city: Santiago del Estero
    Destination location: Terminal de Ómnibus de Santiago del Estero
    Operated by: Flecha BusFlecha Bus
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 30 June at
    Departure city: Santa Fe
    Departure location: Estación Terminal de Ómnibius, Santa Fe
    Arrival time: 1 July at
    Destination city: Santiago del Estero
    Destination location: Terminal de Ómnibus de Santiago del Estero
    Operated by: El PracticoEl Practico
    Vehicle: BusDuration:
  • Departure time: 30 June at
    Departure city: Santa Fe
    Departure location: Estación Terminal de Ómnibius, Santa Fe
    Arrival time: 1 July at
    Destination city: Santiago del Estero
    Destination location: Terminal de Ómnibus de Santiago del Estero
    Operated by: El PracticoEl Practico
    Vehicle: BusDuration:
  • Departure time: 30 June at
    Departure city: Santa Fe
    Departure location: Estación Terminal de Ómnibius, Santa Fe
    Arrival time: 1 July at
    Destination city: Santiago del Estero
    Destination location: Terminal de Ómnibus de Santiago del Estero
    Operated by: Flecha BusFlecha Bus
    Vehicle: BusDuration:
  • Departure time: 30 June at
    Departure city: Santa Fe
    Departure location: Estación Terminal de Ómnibius, Santa Fe
    Arrival time: 1 July at
    Destination city: Santiago del Estero
    Destination location: Terminal de Ómnibus de Santiago del Estero
    Operated by: El PracticoEl Practico
    Vehicle: BusDuration:

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Bus Santa Fe to Santiago del Estero: Trip Overview

Average ticket priceUS$52
Average bus trip duration9h 20m
Number of daily buses1
Earliest bus departure19:50
Distance341 miles
Latest bus departure20:10

Santa Fe to Santiago del Estero Bus

With Busbud, comparing and booking tickets for a bus from Santa Fe to Santiago del Estero is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from Santa Fe to Santiago del Estero will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses travelling from Santa Fe to Santiago del Estero, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Santa Fe, AR - Santiago del Estero

  1. What's the distance between Santa Fe and Santiago del Estero by coach?

    The distance between Santa Fe and Santiago del Estero by coach is approximately 341 miles (549 km).

  2. How can I travel from Santa Fe to Santiago del Estero avoiding air travel?

    You have the option to select the coach for your journey on this route. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
28/06
No data
29/06
No data
Today
US$33
01/07
US$49
02/07
US$48
03/07
No data
04/07
No data
05/07
No data
busbud logoThe cheapest trip from Santa Fe to Santiago del Estero was searched and found on 30 Jun 2025 with a price of US$33

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santa Fe to Santiago del Estero as early as possible.

You can expect to pay from US$33 to US$55 for a bus ticket from Santa Fe to Santiago del Estero based on the last 2 days. You can expect to find the cheapest price for the trip at US$48, which is on 2025-07-02.

Usually Flechabus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Santa Fe to Santiago del Estero.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from Santa Fe to Santiago del Estero, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Santa Fe to Santiago del Estero that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from Santa Fe to Santiago del Estero, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Will you be returning to Santa Fe by bus?

Bus from Santa Fe to Santiago del Estero

Why choose Busbud?

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