Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Terminal de Ómnibus de Santiago del Estero | Estación Terminal de Ómnibus | Cheapest | ||||
| Bus | Terminal de Ómnibus de Santiago del Estero | Estación Terminal de Ómnibus | Fastest |
Last refresh of the prices: Last Wednesday at 10:55 AM -03.
Get from Santiago del Estero to Santa Fe
The journey takes about 9 hours 35 minutes, and with fares starting at just $39, it presents an excellent value for a comfortable ride.
Where are the popular stops in Santiago del Estero and Santa Fe?
Stops in Santiago del Estero
- A
Terminal de Ómnibus de Santiago del Estero
Chacabuco, s/n, 4200 Santiago del Estero - BSta Fe 484, 4200 Santiago del Estero, Santiago del Estero, Argentina
Stops in Santa Fe
- A
Estación Terminal de Ómnibius, Santa Fe
Estación Terminal de Onmibus Belgrano 2900 , S3000GCH Santa Fe, Argentina
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Frequently asked questions about travelling from Santiago del Estero to Santa Fe, AR by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Santiago del Estero to Santa Fe?
The cheapest bus tickets from Santiago del Estero to Santa Fe start from $39. The average price for this route is around $66. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Santiago del Estero to Santa Fe?
The average bus travel time from Santiago del Estero to Santa Fe is 9h 35m, covering a distance of 551 km. The quickest bus can get you there in 9h 5m and is operated by Flechabus.
Which bus companies service the Santiago del Estero to Santa Fe route?
Several major bus companies operate on this route with 1 buses available per day, including services from Flechabus, El Practico.
What are the earliest and latest departure times for the bus from Santiago del Estero to Santa Fe?
The earliest bus departs from Santiago del Estero to Santa Fe at 9:10pm. And the latest bus departs at 10:00pm.
What are the CO₂ emissions for the bus trip from Santiago del Estero to Santa Fe?
A bus trip from Santiago del Estero to Santa Fe generates an estimated 14 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Santiago del Estero to Santa Fe?
According to Busbud customers, the highest-rated bus company on this route is El Practico, with an average rating of 4.5 out of 5 stars based on 556 reviews.
Which bus company has the best Wi-Fi from Santiago del Estero to Santa Fe?
Based on Busbud reviews, the bus company El Practico has the highest Wi-Fi rating with a score of 2.4.
Which bus company has the best on-time performance from Santiago del Estero to Santa Fe?
According to Busbud traveller reviews, the most punctual bus company on this route is El Practico, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Santiago del Estero to Santa Fe?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is El Practico, with a cleanliness rating of 4.7 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Santiago del Estero to Santa Fe, AR was searched and found on Dec 3, 2025 with a price of $47To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santiago del Estero to Santa Fe, AR, as early as possible.
You can expect to pay from $47 to $81 for a bus ticket from Santiago del Estero to Santa Fe, AR based on the last 2 days. You can expect to find the cheapest price for the trip at $47 which is on 2025-12-09.
