Bus Tickets from Santiago, CL to San Nicolás (Biobio Region), CL

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TodayJun 9
from US$15
TomorrowJun 10
WedJun 11
ThuJun 12
FriJun 13
SatJun 14
SunJun 15
MonJun 16

Cheap buses leaving today

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: June 9 at
    Departure city: Santiago
    Departure location: Terminal Sur
    Arrival time: June 10 at
    Destination city: San Nicolás
    Destination location: Terminal de Autobuses de San Nicolas
    Operated by: EME BusEME Bus
    Vehicle: BusDuration:

Last refresh of the prices: Yesterday at 12:43 AM -04.

Prices and availability are subject to change.

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Bus Santiago to San Nicolás: Trip Overview

Average Ticket PriceUS$12
Average Bus Trip Duration4h 16m
Number of daily buses3
Earliest bus departure9:15am
Distance366 km
Latest bus departure10:50pm

Santiago to San Nicolás Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Santiago to San Nicolás.

Bus service from Santiago to San Nicolás will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to San Nicolás from Santiago, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Santiago, CL - San Nicolás (Biobio Region), CL

  1. How long is the trip from Santiago to San Nicolás by bus?

    The typical travel time from Santiago to San Nicolás by bus is around 4h 16m. The fastest bus on this trip will get to San Nicolás in 4h 16m

  2. What is the travel distance from Santiago to San Nicolás?

    The distance between Santiago and San Nicolás is around 374 km (232 miles).

  3. What are the departure and arrival locations for buses traveling from Santiago to San Nicolás?

    Buses traveling this route start their trip at Terminal Sur, in Santiago, and end it at Terminal de Autobuses de San Nicolas, in San Nicolás.

  4. What is the cheapest way to go from Santiago to San Nicolás?

    Taking the bus is the most budget-friendly option to travel from Santiago to San Nicolás. The ticket price for this bus starts at US$12, making this your best choice for this trip.

  5. How much does the bus ticket cost from Santiago to San Nicolás?

    Taking the bus from Santiago to San Nicolás costs on average US$12.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06-07
US$11
06-08
US$14
Today
US$11
06-10
No data
06-11
No data
06-12
No data
06-13
No data
06-14
No data
busbud logoThe cheapest trip from Santiago to San Nicolás was searched and found on Jun 7, 2025 with a price of US$11

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santiago to San Nicolás, as early as possible.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Santiago to San Nicolás but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from Santiago to San Nicolás, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Santiago to San Nicolás.

Tune out to the fine sounds of your best music playlist on your bus trip from Santiago to San Nicolás while indulging in miles on end of beautiful scenic views.

Did you know?

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Will you be returning to Santiago by bus?

Bus from Santiago to San Nicolás

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