Find coaches from Santiago, CL to San Nicolás (Biobio Region), CL

Find affordable coach tickets from Santiago, CL to San Nicolás (Biobio Region), CL with flexible options. Book your journey now

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Today14 Jun
Tomorrow15 Jun
from US$13
Mon16 Jun
from US$12
Tue17 Jun
Wed18 Jun
Thu19 Jun
from US$19
Fri20 Jun
Sat21 Jun

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 15 June at
    Departure city: Santiago
    Departure location: Terminal Sur
    Arrival time: 15 June at
    Destination city: San Nicolás
    Destination location: Terminal de Autobuses de San Nicolas
    Operated by: EME BusEME Bus
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 15 June at
    Departure city: Santiago
    Departure location: Terminal Sur
    Arrival time: 15 June at
    Destination city: San Nicolás
    Destination location: Terminal de Autobuses de San Nicolas
    Operated by: EME BusEME Bus
    Vehicle: BusDuration:
  • Departure time: 15 June at
    Departure city: Santiago
    Departure location: Terminal Sur
    Arrival time: 15 June at
    Destination city: San Nicolás
    Destination location: Terminal de Autobuses de San Nicolas
    Operated by: EME BusEME Bus
    Vehicle: BusDuration:
  • Departure time: 15 June at
    Departure city: Santiago
    Departure location: Terminal Sur
    Arrival time: 15 June at
    Destination city: San Nicolás
    Destination location: Terminal de Autobuses de San Nicolas
    Operated by: EME BusEME Bus
    Vehicle: BusDuration:
  • Departure time: 15 June at
    Departure city: Santiago
    Departure location: Terminal Sur
    Arrival time: 15 June at
    Destination city: San Nicolás
    Destination location: Terminal de Autobuses de San Nicolas
    Operated by: EME BusEME Bus
    Vehicle: BusDuration:

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Bus Santiago to San Nicolás: Trip Overview

Average ticket priceUS$13
Average bus trip duration4h 16m
Number of daily buses3
Earliest bus departure09:15
Distance227 miles
Latest bus departure22:50

Santiago to San Nicolás Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Santiago to San Nicolás.

Bus service from Santiago to San Nicolás will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to San Nicolás from Santiago, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Santiago, CL - San Nicolás (Biobio Region), CL

  1. How much does the Santiago San Nicolás coach trip cost?

    For coach travel from Santiago to San Nicolás, ticket prices typically start at US$12 and can reach a maximum of US$19. The cost of tickets can fluctuate based on factors like the time of day, the company, and the class you choose. Use Busbud to compare prices and amenities offered by different companies, ensuring you find the most favorable deals and promotions.

  2. How long is the coach ride from Santiago to San Nicolás?

    The average duration for a trip from Santiago to San Nicolás by coach is around 4h 16m. If you're looking for the fastest trip, you can get there in just about 4h 16m. Please be aware that the time it takes for your journey may vary depending on the traffic conditions along the route.

  3. When is the first coach from Santiago to San Nicolás?

    The first departure to San Nicolás is at 09:15. Times and services may vary during weekends and holidays.

  4. How far is San Nicolás from Santiago by coach?

    The distance between Santiago and San Nicolás by coach is approximately 232 miles (374 km).

  5. Is there a way to reach San Nicolás from Santiago without a car?

    You can travel to San Nicolás from Santiago by coach, which provides a smooth ride and an affordable and convenient trip. Depending on your preferences, another alternative is to explore ridesharing trips.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
12/06
No data
13/06
No data
Today
No data
15/06
US$12
16/06
US$11
17/06
No data
18/06
No data
19/06
US$18
busbud logoThe cheapest trip from Santiago to San Nicolás was searched and found on 16 Jun 2025 with a price of US$11

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santiago to San Nicolás as early as possible.

You can expect to pay from US$11 to US$23 for a bus ticket from Santiago to San Nicolás based on the last 2 days. You can expect to find the cheapest price for the trip at US$11, which is on 2025-06-16.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Santiago to San Nicolás but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from Santiago to San Nicolás, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Santiago to San Nicolás.

Tune out to the fine sounds of your best music playlist on your bus trip from Santiago to San Nicolás while indulging in miles on end of beautiful scenic views.

Did you know?

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Will you be returning to Santiago by bus?

Bus from Santiago to San Nicolás

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