Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Greyhound Station | 1116 Woodruff Rd | CheapestFastest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Seattle–Tacoma Int'l Airport (SEA) | 1116 Woodruff Rd | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | University of Washington | 1116 Woodruff Rd | No tags |
Last refresh of the prices: Last Saturday at 5:41 PM PST.
Compare 2 ways to go from Seattle to Greenville
Among the sustainable travel choices, the Bus stands out as a good way to reach Greenville. The journey takes about 3 days, 12 hours 10 minutes, and with fares starting at just $405, it presents an excellent value for a comfortable ride.
Where are the popular stops in Seattle and Greenville?
Stops in Seattle
- A503 S Royal Brougham Way, Seattle, WA 98134, USA
- C
Washington State Convention Center
705 Pike St, Seattle WA 98101, USA, , Pick-up is at the Charter Bus Loading Zone on 8th Avenue at the corner of 8th Ave. and Pike Street. - D2001 W Garfield St, Seattle WA 98119, USA
- E
Pier 66
2203 Alaskan Way, Seattle WA 98121, USA - F
International District
700-822 5th Ave S, Seattle, WA 98104, USA
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Frequently asked questions about travelling from Seattle to Greenville, SC by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Seattle to Greenville?
The cheapest bus tickets from Seattle to Greenville start from $405. The average price for this route is around $442. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Seattle to Greenville?
The average bus travel time from Seattle to Greenville is 3d 12h, covering a distance of 3588 km. The quickest bus can get you there in 3d 5h and is operated by Greyhound.
Which bus companies service the Seattle to Greenville route?
What are the earliest and latest departure times for the bus from Seattle to Greenville?
The earliest bus departs from Seattle to Greenville at 2:40pm. And the latest bus departs at 10:50pm.
What are the CO₂ emissions for the bus trip from Seattle to Greenville?
A bus trip from Seattle to Greenville generates an estimated 90 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Seattle to Greenville?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87463 reviews.
Which bus company has the best Wi-Fi from Seattle to Greenville?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from Seattle to Greenville?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Seattle to Greenville?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Seattle to Greenville, SC was searched and found on Jan 12, 2026 with a price of $322To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Seattle to Greenville, SC, as early as possible.
You can expect to pay from $322 to $338 for a bus ticket from Seattle to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at $338 which is on 2026-01-13.
What's the cheapest way to go from Seattle to Greenville, SC?
The Bus is the cheapest travel choice for this destination
