Bus Tickets from Seattle to Greenville, SC

Previously seen trips

Next departures for Seattle to Greenville on November 4
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound + FlixBus
    		Greyhound Station
    		1116 Woodruff RdNo tags
    FlixBus + Greyhound
      		Greyhound Station
      		1116 Woodruff RdNo tags
      Greyhound + FlixBus
        		Seattle–Tacoma Int'l Airport (SEA)
        		1116 Woodruff RdNo tags
        FlixBus + Greyhound
          		Seattle–Tacoma Int'l Airport (SEA)
          		1116 Woodruff RdNo tags
          FlixBus + Greyhound
            		University of Washington
            		1116 Woodruff RdNo tags

            Accepted payments

            • Visa
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            • American Express
            • China Union Pay
            • Diners Club Canada
            • Discover Click to Pay
            • JCB payment
            • Klarna (Pay over time)
            • Google Pay

            Compare 2 ways to go from Seattle to Greenville

            We recommend taking the bus

            Among the sustainable travel choices, the bus stands out as the good way to reach Greenville. The journey takes about 3 days, 12 hours 15 minutes and with fares starting at just $258, it presents an excellent value for a comfortable ride.

            3bus per day
            3d 12hAverage Duration
            2225 milesDistance
            90kgCO₂ emissions
            Bus
            		Average Price$258 - $431Average Duration3d 12h
            90kg CO₂e
            Train
            		Average Price$741 - $2,350Average Duration3d 9h
            326kg CO₂e

            Bus Seattle to Greenville, SC: Trip Overview

            Average ticket price$312
            Average bus trip duration3d 12h
            Number of daily buses3
            Earliest bus departure2:45pm
            Distance2224 miles (3587 km)
            Latest bus departure10:50pm

            Seattle to Greenville Bus

            Busbud helps you find a bus from Seattle to Greenville. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

            Bus service from Seattle to Greenville will be provided by the most trusted bus companies.

            Whether it is cheap bus tickets or more luxurious buses going to Greenville from Seattle, we help you find what you're looking for based on how much of a budget you have.

            Frequently asked questions for your trip Seattle - Greenville, SC

            Find cheapest prices for buses

            Price is for a one-way ticket for one passenger and based on past searches.

            Best price found
            11/02
            No data
            11/03
            $264
            Today
            No data
            11/05
            No data
            11/06
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            11/07
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            11/08
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            11/09
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            busbud logoThe cheapest trip from Seattle to Greenville, SC was searched and found on Nov 3, 2025 with a price of $264

            To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Seattle to Greenville, SC, as early as possible.

            About Bus Travel

            Bus Travel Tips

            Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Seattle and Greenville!

            Much more than a mere vehicle taking you from Seattle to Greenville, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

            Buses are energy-efficient. Carrying a passenger over 100 kms by bus only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Seattle to Greenville.

            Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Seattle to Greenville.

            Did you know?

            It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

            9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

            The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

            What's the cheapest way to go from Seattle to Greenville, SC?

            busbud logoThe bus is the cheapest travel choice for this destination

            Will you be returning to Seattle by bus?

            Bus from Greenville, SC to Seattle

            You can also go to Greenville, SC by train

            Train from Seattle to Greenville, SC

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