Bus Tickets from Sioux Falls to Des Moines

Previously seen trips

Next departures for Sioux Falls to Des Moines on October 12
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Jefferson Lines
Sioux Falls
Des MoinesNo tags
Jefferson Lines
Sioux Falls
Des MoinesNo tags
Jefferson Lines
Sioux Falls
Des MoinesNo tags
Jefferson Lines
Sioux Falls
Des MoinesNo tags
Jefferson Lines
Sioux Falls
Des MoinesNo tags

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Bus Sioux Falls to Des Moines: Trip Overview

Average Ticket PriceUS$173
Average Bus Trip Duration16h 30m
Number of daily buses3
Earliest bus departure10:00am
Distance339 km
Latest bus departure8:05pm

Sioux Falls to Des Moines Bus

With Busbud, comparing and booking tickets for a bus from Sioux Falls to Des Moines is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from Sioux Falls to Des Moines will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to Des Moines from Sioux Falls, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Sioux Falls - Des Moines

  1. How far is Sioux Falls from Des Moines?

    The distance between Sioux Falls and Des Moines is approximately 330 km (205 miles).

  2. What are the departure and arrival locations for buses traveling from Sioux Falls to Des Moines?

    Buses departing from Jefferson Lines Station I-29 & Maple St in Sioux Falls will take you to Jefferson/Trailways Depot in Des Moines.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
10-09
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10-10
US$168
Today
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10-12
No data
10-13
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10-14
US$168
10-15
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10-16
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busbud logoThe cheapest trip from Sioux Falls to Des Moines was searched and found on Oct 10, 2025 with a price of US$168

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Sioux Falls to Des Moines, as early as possible.

You can expect to pay from US$168 to US$168 for a bus ticket from Sioux Falls to Des Moines based on the last 2 days. You can expect to find the cheapest price for the trip at US$168 which is on 2025-10-14.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Sioux Falls to Des Moines.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from Sioux Falls to Des Moines, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Sioux Falls to Des Moines.

Make a music playlist for your bus ride from Sioux Falls to Des Moines, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Will you be returning to Sioux Falls by bus?

Bus from Des Moines to Sioux Falls

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