Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Gateway Station | Columbus (E Mound St) | Cheapest | ||||
| Bus | Gateway Station | Columbus (E Mound St) | Fastest | ||||
 | Bus | Gateway Station | 100 E Rich St | No tags | ||||
| Bus | Gateway Station | Columbus (E Mound St) | No tags |
Last refresh of the prices: Today at 4:21 AM CST.
Get from St. Louis to Columbus
The journey takes about 10 hours 55 minutes, and with fares starting at just $77, it presents an excellent value for a comfortable ride.
Where are the popular stops in St. Louis and Columbus?
Stops in Columbus
- A
Columbus Bus Station
25 E Rich St, Columbus, OH 43205, USA
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Frequently asked questions about travelling from St. Louis to Columbus, OH by bus
What is the distance between St. Louis and Columbus?
It's about 638 km (396 miles) from St. Louis to Columbus.
What are the departure and arrival locations for buses traveling from St. Louis to Columbus?
Buses traveling this route start their trip at Gateway Station, in St. Louis, and end it at Columbus Bus Station, in Columbus.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from St. Louis to Columbus, OH was searched and found on Nov 25, 2025 with a price of $96To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St. Louis to Columbus, OH, as early as possible.
You can expect to pay from $96 to $236 for a bus ticket from St. Louis to Columbus, OH based on the last 2 days. You can expect to find the cheapest price for the trip at $99 which is on 2025-11-26.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
