What is the distance between St. Louis and Columbus?

The distance separating St. Louis and Columbus is 396 miles (638 km).

What are the departure and arrival stations when taking the bus from St. Louis to Columbus?

Buses going from St. Louis to Columbus start their journey at Gateway Station and reach their destination at Columbus Bus Station.

Bus St. Louis to Columbus from $47 | Refundable Tickets

Next bus departures

Next departures for St. Louis to Columbus on November 28
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	8:45am	Gateway Station	11h 20m	9:05pm	Columbus (E Mound St)	Cheapest
Bus	1:55pm	Gateway Station	9h 40m	12:35am	Columbus (E Mound St)	Fastest
Bus	9:30am	Gateway Station	17h 10m	3:40am	100 E Rich St	No tags
Bus	2:00am	Gateway Station	10h 55m	1:55pm	Columbus (E Mound St)	No tags

Last refresh of the prices: Today at 4:21 AM CST.

Get from St. Louis to Columbus

This route is served by bus only

The journey takes about 10 hours 55 minutes and with fares starting at just $54, it presents an excellent value for a comfortable ride.

3bus per day

10h 55mAverage Duration

396 milesDistance

16kgCO₂ emissions

Where are the popular stops in St. Louis and Columbus?

Stops in St. Louis

A
Gateway Station
430 S 15th St, St Louis, MO 63103
Visit page

Stops in Columbus

A
Columbus Bus Station
25 E Rich St, Columbus, OH 43205, USA

Compare bus companies

Greyhound

3.5/587,394 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

FlixBus

3.5/511,442 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about traveling from St. Louis to Columbus, OH by bus

What is the distance between St. Louis and Columbus?
What are the departure and arrival stations when taking the bus from St. Louis to Columbus?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/23

No data

11/24

$77

Today

$66

11/26

$68

11/27

No data

11/28

$68

11/29

No data

11/30

$70

The cheapest trip from St. Louis to Columbus, OH was searched and found on Nov 25, 2025 with a price of $66

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St. Louis to Columbus, OH, as early as possible.

You can expect to pay from $66 to $163 for a bus ticket from St. Louis to Columbus, OH based on the last 2 days. You can expect to find the cheapest price for the trip at $68 which is on 2025-11-26.

Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.