Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Syracuse (Regional Transportation Center) | Columbus (E Mound St) | Cheapest | ||||
| Bus | Syracuse (Regional Transportation Center) | Columbus (E Mound St) | Fastest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Syracuse (Regional Transportation Center) | 100 E Rich St | No tags | ||||
| Bus | Syracuse (Regional Transportation Center) | Columbus (E Mound St) | No tags |
Last refresh of the prices: Last Friday at 8:58 PM EDT.
Get from Syracuse to Columbus
The journey takes about 19 hours 20 minutes, and with fares starting at just $111, it presents an excellent value for a comfortable ride.
Where are the popular stops in Syracuse and Columbus?
Stops in Syracuse
- A
Regional Transportation Center
1 Walsh Circle Ste 30, Syracuse, NY 13208 - CBus stops at Schine Student Center across the street from the Sheraton Parking Garage., Schine Student Center, 303 University Pl, Syracuse, NY 13210
- D
Syracuse University - Lyman Hall
College Place, Syracuse, NY 13210, USA - E
New York State Fairgrounds
581 State Fair Blvd, Syracuse, NY 13209, USA - F
Syracuse, NY
349-399 US-11, Syracuse, NY 13202, USA
Stops in Columbus
- A
Columbus Bus Station
25 E Rich St, Columbus, OH 43205, USA
Compare bus companies
Based on 87529 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi‑Fi. Greyhound ticket prices on this trip start at $111
Frequently asked questions about travelling from Syracuse, US to Columbus, OH by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Syracuse to Columbus?
The cheapest bus tickets from Syracuse to Columbus start from $111. The average price for this route is around $219. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Syracuse to Columbus?
The average bus travel time from Syracuse to Columbus is 19h 20m, covering a distance of 666 km. The quickest bus can get you there in 17h 25m and is operated by Greyhound.
Which bus companies service the Syracuse to Columbus route?
Several major bus companies operate on this route with 5 buses available per day.
What are the earliest and latest departure times for the bus from Syracuse to Columbus?
The earliest bus departs from Syracuse to Columbus at 3:55am. And the latest bus departs at 9:00pm.
What are the CO₂ emissions for the bus trip from Syracuse to Columbus?
A bus trip from Syracuse to Columbus generates an estimated 17 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Syracuse, US to Columbus, OH was searched and found on Mar 24, 2026 with a price of $154To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Syracuse, US to Columbus, OH, as early as possible.
You can expect to pay from $154 to $357 for a bus ticket from Syracuse, US to Columbus, OH based on the last 2 days. You can expect to find the cheapest price for the trip at $154 which is on 2026-03-24.
