Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | Tampa Bus Station | Durham Greyhound Bus Station | Cheapest | ||||
 | Bus | Tampa Bus Station | Durham Greyhound Bus Station | Fastest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Tampa Bus Station | Durham Greyhound Bus Station | No tags | ||||
| Bus | Tampa Bus Station | Durham Greyhound Bus Station | No tags | ||||
| Bus | Tampa Bus Station | Durham Greyhound Bus Station | No tags |
Last refresh of the prices: Today at 5:22 PM EST.
Compare 2 ways to go from Tampa to Durham
Among the sustainable travel choices, the Train stands out as a good way to reach Durham. The journey takes about 17 hours 41 minutes, and with fares starting at just $95, it presents an excellent value for a comfortable ride.
Where are the popular stops in Tampa and Durham?
Stops in Tampa
- A
Tampa 13th Avenue Bus Stop (McDonald's)
2101 E 13th Ave (McDonald's), Tampa, FL 33605 - B
Tampa USF, FL
3801 USF Holly Drive, Tampa., FL 33620, USA - C
Greyhound Station
610 E Polk St, Tampa, FL 33602, USA - D
E Sligh Ave
11555 E Sligh Ave, Seffner, FL 33584, USA - E
N Marion St & E Laurel St
551 E Laurel St, Tampa, FL 33602, USA - F
Port of Tampa
200-298 FL-60, Tampa, FL 33602, USA
Stops in Durham
- A515 W Pettigrew St , Durham, NC 27703
- B
Compare Foods Durham
2000-2004 NC-55, Durham, NC 27704, USA - C
Durham Compare Foods Durham
2000 Avondale Dr, Durham, NC 27704, USA - D
Durham, NC
E Main St at Roxboro St (WB), Durham, NC 27701, USA
Compare bus companies
Frequently asked questions about travelling from Tampa to Durham, NC, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Tampa to Durham?
The cheapest bus tickets from Tampa to Durham start from $183. The average price for this route is around $279. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Tampa to Durham?
The average bus travel time from Tampa to Durham is 22h, covering a distance of 955 km. The quickest bus can get you there in 18h 10m and is operated by FlixBus.
Which bus companies service the Tampa to Durham route?
What are the earliest and latest departure times for the bus from Tampa to Durham?
The earliest bus departs from Tampa to Durham at 6:10am. And the latest bus departs at 10:35pm.
What are the CO₂ emissions for the bus trip from Tampa to Durham?
A bus trip from Tampa to Durham generates an estimated 24 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Tampa to Durham?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 12050 reviews.
Which bus company has the best Wi-Fi from Tampa to Durham?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from Tampa to Durham?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Tampa to Durham?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Tampa to Durham, NC, US was searched and found on Jan 30, 2026 with a price of $315To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Tampa to Durham, NC, US, as early as possible.
You can expect to pay from $315 to $344 for a bus ticket from Tampa to Durham, NC, US based on the last 2 days. You can expect to find the cheapest price for the trip at $315 which is on 2026-01-30.
