Cheap buses leaving Tuesday
One passenger / one way
- This trip is recommended because it is the: Cheapest
- This trip is recommended because it is the: Fastest
- Departure time: May 27 atDeparture city: TupeloDeparture location: Tupelo (Brothers Quick Stop)Arrival time: May 28 atDestination city: ChicagoDestination location: Downtown Greyhound StationOperated by: Greyhound Lines, Inc.
Vehicle: BusDuration:
Last refresh of the prices: Yesterday at 3:52 PM CDT.
Prices and availability are subject to change.
Accepted payments
Bus Tupelo to Chicago: Trip Overview
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Based on 86997 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at US$93.00
Tupelo to Chicago Bus
With Busbud, comparing and booking tickets for a bus from Tupelo to Chicago is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
We make sure you can find a bus service from Tupelo to Chicago from the most reliable bus companies operating this trip.
Discover how much the bus trip from Tupelo to Chicago will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.
Frequently asked questions on the trip Tupelo - Chicago
How long is the bus trip from Tupelo to Chicago?
The typical travel time from Tupelo to Chicago by bus is around 1d. If you're looking for the fastest way to get there, you'll find a bus doing the trip in about 16h 25m.
How far is Tupelo from Chicago?
It's about 853 km (529 miles) from Tupelo to Chicago.
What is the cheapest way to travel from Tupelo to Chicago?
The least expensive way to go from Tupelo to Chicago would be going by bus. The ticket price for this bus starts at US$93, making this your best choice for this trip.
How much does it cost to take the bus from Tupelo to Chicago?
Taking the bus from Tupelo to Chicago costs on average US$142.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Tupelo to Chicago was searched and found on May 27, 2025 with a price of US$124To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Tupelo to Chicago, as early as possible.
You can expect to pay from US$124 to US$270 for a bus ticket from Tupelo to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at US$124 which is on 2025-05-27.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while travelling from Tupelo to Chicago.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
Start sightseeing the minute your bus leaves the station. If you're on the night bus from Tupelo to Chicago, get comfy and count the stars.
Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Tupelo to Chicago will emit less CO2 than a car or an airplane.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Tupelo to Chicago.
Did you know?
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
Top travelled bus routes
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