Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Tupelo (Brothers Quick Stop) | New Orleans Bus Station | No tags | ||||
| Bus | Tupelo (Brothers Quick Stop) | New Orleans Bus Station | No tags | ||||
| Bus | Tupelo (Brothers Quick Stop) | New Orleans Bus Station | No tags | ||||
| Bus | Tupelo (Brothers Quick Stop) | New Orleans Bus Station | No tags | ||||
| Bus | Tupelo (Brothers Quick Stop) | New Orleans Bus Station | No tags |
Get from Tupelo to New Orleans
This route is served by bus only
The journey takes about 17 hours 40 minutes, and with fares starting at just $137, it presents an excellent value for a comfortable ride.
3bus per day
17h 40mAverage Duration
495 kmDistance
12kgCO₂ emissions
Compare bus companies
3.5 out of 5 stars3.5/587,398 reviews
Based on 87398 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $137
US Bus Companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad
Frequently asked questions about travelling from Tupelo to New Orleans by bus
How far is Tupelo from New Orleans?
The distance between Tupelo and New Orleans is approximately 495 km (307 miles).
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11-25
$268
11-26
$268
Today
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11-28
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11-29
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11-30
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12-01
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12-02
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The cheapest trip from Tupelo to New Orleans was searched and found on Nov 25, 2025 with a price of $268To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Tupelo to New Orleans, as early as possible.
