Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Wilmington (Cape Fear Public Transit) | Winston Salem Greyhound Bus Station | CheapestFastest | ||||
| Bus | Wilmington (Cape Fear Public Transit) | Winston Salem Greyhound Bus Station | No tags |
Last refresh of the prices: Last Friday at 8:06 AM EST.
Get from Wilmington to Winston-Salem
The journey takes about 14 hours 50 minutes, and with fares starting at just $91, it presents an excellent value for a comfortable ride.
Where are the popular stops in Wilmington and Winston-Salem?
Stops in Wilmington
- A
Cape Fear Public Transit Bus Stop
505 Cando St, Wilmington, NC 28405
Stops in Winston-Salem
- A
Winston Salem Greyhound Bus Station
100 W 5th St, Winston Salem, NC 27101 - B
E Sprague St
841 E Sprague St, Winston-Salem, NC 27107, USA - C
Winston-Salem Bus Stop
2500 Old Lexington Rd, Winston-Salem, NC 27107, USA - D
1237 Silas Creek Pkwy
1237 Silas Creek Pkwy., Winston-Salem, NC 27127 (Hong Kong King Buffet)
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Frequently asked questions about travelling from Wilmington, NC to Winston-Salem by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Wilmington to Winston-Salem?
The cheapest bus tickets from Wilmington to Winston-Salem start from $91. The average price for this route is around $109. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Wilmington to Winston-Salem?
The average bus travel time from Wilmington to Winston-Salem is 14h 50m, covering a distance of 298 km. The quickest bus can get you there in 7h 40m and is operated by Greyhound.
Which bus companies service the Wilmington to Winston-Salem route?
What are the earliest and latest departure times for the bus from Wilmington to Winston-Salem?
The earliest bus departs from Wilmington to Winston-Salem at 7:40am. And the latest bus departs at 4:10pm.
What are the CO₂ emissions for the bus trip from Wilmington to Winston-Salem?
A bus trip from Wilmington to Winston-Salem generates an estimated 7 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Wilmington to Winston-Salem?
According to Busbud customers, the highest-rated bus company on this route is Amtrak, with an average rating of 4.1 out of 5 stars based on 5733 reviews.
Which bus company has the best Wi-Fi from Wilmington to Winston-Salem?
Based on Busbud reviews, the bus company Amtrak has the highest Wi-Fi rating with a score of 3.6.
Which bus company has the best on-time performance from Wilmington to Winston-Salem?
According to Busbud traveller reviews, the most punctual bus company on this route is Amtrak, with a punctuality rating of 3.8 out of 5 stars.
Which bus company has the cleanest buses from Wilmington to Winston-Salem?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Amtrak, with a cleanliness rating of 4.5 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Wilmington, NC to Winston-Salem was searched and found on Jan 30, 2026 with a price of $74To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Wilmington, NC to Winston-Salem, as early as possible.
You can expect to pay from $74 to $90 for a bus ticket from Wilmington, NC to Winston-Salem based on the last 2 days. You can expect to find the cheapest price for the trip at $74 which is on 2026-01-30.
