Find coaches from Chicago to Panama City, US

Previously seen journeys

Next departures from Chicago to Panama City on 4 October
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound
Downtown Greyhound Station
Panama City Beach StationNo tags
Greyhound
Downtown Greyhound Station
Panama City Beach StationNo tags
Greyhound
537-517 W. Jackson Blvd
Panama City Beach StationNo tags
FlixBus + Greyhound
Chicago 95Th & Dan Ryan
Panama City Beach StationNo tags
Greyhound
Downtown Greyhound Station
Panama City Beach StationNo tags

Accepted payments

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Bus Chicago to Panama City, US: Trip Overview

Average ticket priceUS$167
Average bus trip duration1d 4h
Number of daily buses6
Earliest bus departure00:30
Distance802 miles
Latest bus departure23:59

Chicago to Panama City Bus

With Busbud, comparing and booking tickets for a bus from Chicago to Panama City is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from Chicago to Panama City will be provided by the most trusted bus companies.

Discover how much the bus trip from Chicago to Panama City will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Chicago - Panama City, US

  1. How far is Panama City from Chicago by coach?

    The journey from Chicago to Panama City by coach covers an approximate distance of 815 miles (1314 km).

  2. Is there a way to reach Panama City from Chicago without flying?

    To travel from Chicago to Panama City without flying, you can take the coaches. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
01/10
No data
02/10
US$141
Today
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04/10
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05/10
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06/10
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07/10
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08/10
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busbud logoThe cheapest trip from Chicago to Panama City, US was searched and found on 2 Oct 2025 with a price of US$141

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to Panama City, US as early as possible.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Chicago to Panama City.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from Chicago to Panama City, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Chicago to Panama City will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Make a music playlist for your bus ride from Chicago to Panama City, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Will you be returning to Chicago by bus?

Bus from Panama City, US to Chicago

Why choose Busbud?

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