Find coaches from Detroit, MI to Tupelo

Next departures

Next departures from Detroit to Tupelo on 4 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.
    		Detroit Bus Station
    		Tupelo (Brothers Quick Stop)Cheapest
    Greyhound Lines, Inc.
      		Detroit Bus Station
      		Tupelo (Brothers Quick Stop)Fastest
      Greyhound Lines, Inc.
        		Detroit Bus Station
        		Tupelo (Brothers Quick Stop)No tags
        Greyhound Lines, Inc.
          		Detroit Bus Station
          		Tupelo (Brothers Quick Stop)No tags

          Last refresh of the prices: Yesterday at 18:50 EDT.

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          Get from Detroit to Tupelo

          This route is served by bus only

          The journey takes about 1 day, 40 minutes, and with fares starting at just US$92, it presents an excellent value for a comfortable ride.

          4bus per day
          1d Average duration
          636 milesDistance
          26kgCO₂ emissions

          Bus Detroit, MI to Tupelo: Trip Overview

          Average ticket priceUS$141
          Average bus trip duration1d
          Number of daily buses4
          Earliest bus departure06:40
          Distance636 miles
          Latest bus departure23:25

          Detroit to Tupelo Bus

          With Busbud, comparing and booking tickets for a bus from Detroit to Tupelo is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

          We make sure you can find a bus service from Detroit to Tupelo from the most reliable bus companies operating this trip.

          Whether it is cheap bus tickets or more luxurious buses going to Tupelo from Detroit, we help you find what you're looking for based on how much of a budget you have.

          Frequently asked questions on the trip Detroit, MI - Tupelo

          1. What's the distance between Detroit and Tupelo by coach?

            The journey from Detroit to Tupelo by coach covers an approximate distance of 636 miles (1026 km).

          2. What is the best way to go from Detroit to Tupelo without flying?

            To travel from Detroit to Tupelo without flying, you can take the coaches. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You might also find carpooling options to travel between the two cities.

          Find cheapest prices for buses

          Price is for a one-way ticket for one passenger and based on past searches.

          Best price found
          30/10
          US$116
          31/10
          US$222
          Today
          US$191
          02/11
          US$168
          03/11
          US$122
          04/11
          US$124
          05/11
          No data
          06/11
          No data
          busbud logoThe cheapest trip from Detroit, MI to Tupelo was searched and found on 30 Oct 2025 with a price of US$116

          To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Detroit, MI to Tupelo as early as possible.

          You can expect to pay from US$116 to US$231 for a bus ticket from Detroit, MI to Tupelo based on the last 2 days. You can expect to find the cheapest price for the trip at US$122, which is on 2025-11-03.

          About Bus Travel

          Bus Travel Tips

          Meet and talk to locals at the bus stations while travelling from Detroit to Tupelo.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

          Start sightseeing the minute your bus leaves the station. If you're on the night bus from Detroit to Tupelo, get comfy and count the stars.

          Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Detroit to Tupelo.

          Make a music playlist for your bus ride from Detroit to Tupelo, and enjoy the scenery to tunes from your own personal soundtrack.

          Did you know?

          One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

          It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

          The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

          Will you be returning to Detroit, MI by bus?

          Bus from Tupelo to Detroit, MI

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