Bus Detroit to Tupelo: Trip Overview
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Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Detroit to Tupelo Bus
With Busbud, comparing and booking tickets for a bus from Detroit to Tupelo is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
We make sure you can find a bus service from Detroit to Tupelo from the most reliable bus companies operating this trip.
Whether it is cheap bus tickets or more luxurious buses going to Tupelo from Detroit, we help you find what you're looking for based on how much of a budget you have.
Frequently asked questions for your trip Detroit (MI) - Tupelo
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Detroit to Tupelo was searched and found on Jun 5, 2025 with a price of $173To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Detroit to Tupelo, as early as possible.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while traveling from Detroit to Tupelo.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
Start sightseeing the minute your bus leaves the station. If you're on the night bus from Detroit to Tupelo, get comfy and count the stars.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Detroit to Tupelo.
Make a music playlist for your bus ride from Detroit to Tupelo, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!
Top traveled bus routes
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Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.
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Popular Buses Connecting Detroit
Buses Leaving from Detroit
Buses Going to Detroit
Popular Buses Connecting Tupelo
Buses Leaving from Tupelo
- Bus from Tupelo to Gainesville
- Bus Tupelo - Gainesville
- Tupelo - Milwaukee
- Bus from Tupelo to Jackson
- Bus Tupelo - Memphis
- Tupelo - Jackson
- Bus from Tupelo to Atlanta
- Bus Tupelo - Chicago
- Tupelo - Nashville
- Bus from Tupelo to Birmingham
- Bus Tupelo - Grand Rapids
- Tupelo - Dallas
- Bus from Tupelo to Tampa
- Bus Tupelo - Meridian
- Tupelo - San Diego
Buses Going to Tupelo
- Bus from Nashville to Tupelo
- Bus Harrisburg - Tupelo
- Memphis - Tupelo
- Bus from Atlanta to Tupelo
- Bus Biloxi - Tupelo
- Dallas - Tupelo
- Bus from Houston to Tupelo
- Bus St Louis - Tupelo
- Tampa - Tupelo
- Bus from Birmingham to Tupelo
- Bus Jackson - Tupelo
- Chicago - Tupelo
- Bus from New York to Tupelo
- Bus Orlando - Tupelo
- Meridian - Tupelo