Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Detroit Bus Station | Tupelo (Brothers Quick Stop) | No tags | ||||
| Bus | Detroit Bus Station | Tupelo (Brothers Quick Stop) | No tags | ||||
| Bus | Detroit Bus Station | Tupelo (Brothers Quick Stop) | No tags | ||||
| Bus | Detroit Bus Station | Tupelo (Brothers Quick Stop) | No tags | ||||
FlixBus + Greyhound | Bus | Detroit Bus Station | Tupelo (Brothers Quick Stop) | No tags |
Get from Detroit to Tupelo
The journey takes about 23 hours 10 minutes, and with fares starting at just $145, it presents an excellent value for a comfortable ride.
Compare bus companies
Based on 87532 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi‑Fi. Greyhound ticket prices on this trip start at $145
Frequently asked questions about travelling from Detroit, MI to Tupelo by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Detroit to Tupelo?
The cheapest bus tickets from Detroit to Tupelo start from $145. The average price for this route is around $162. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Detroit to Tupelo?
The average bus travel time from Detroit to Tupelo is 23h 10m, covering a distance of 1025 km. The quickest bus can get you there in 19h 20m and is operated by Greyhound.
Which bus companies service the Detroit to Tupelo route?
Several major bus companies operate on this route with 4 buses available per day.
What are the earliest and latest departure times for the bus from Detroit to Tupelo?
The earliest bus departs from Detroit to Tupelo at 7:15am. And the latest bus departs at 11:15pm.
What are the CO₂ emissions for the bus trip from Detroit to Tupelo?
A bus trip from Detroit to Tupelo generates an estimated 25.6164 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Detroit, MI to Tupelo was searched and found on Apr 6, 2026 with a price of $140To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Detroit, MI to Tupelo, as early as possible.
You can expect to pay from $140 to $171 for a bus ticket from Detroit, MI to Tupelo based on the last 2 days. You can expect to find the cheapest price for the trip at $153 which is on 2026-04-09.
