Find coaches from Greenville, SC to Gainesville, FL

Previously seen journeys

Next departures from Greenville to Gainesville on 13 October
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus
1116 Woodruff Rd
Rosa Parks StationNo tags
Greyhound + FlixBus
1116 Woodruff Rd
Gainesville Bus StopNo tags
FlixBus + Greyhound
1116 Woodruff Rd
Rosa Parks StationNo tags
Greyhound + FlixBus
1116 Woodruff Rd
Rosa Parks StationNo tags
FlixBus + Greyhound
1116 Woodruff Rd
Gainesville Bus StopNo tags

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Bus Greenville, SC to Gainesville, FL: Trip Overview

Average ticket priceUS$72
Average bus trip duration15h 15m
Number of daily buses8
Earliest bus departure07:40
Distance359 miles
Latest bus departure22:00

Greenville to Gainesville Bus

With Busbud, comparing and booking tickets for a bus from Greenville to Gainesville is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from Greenville to Gainesville from the most reliable bus companies operating this trip.

Discover how much the bus trip from Greenville to Gainesville will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Greenville, SC - Gainesville, FL

  1. How far is Gainesville from Greenville by coach?

    The journey from Greenville to Gainesville by coach covers an approximate distance of 359 miles (579 km).

  2. Is there a way to reach Gainesville from Greenville without flying?

    You can choose the coach to travel this route. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11/10
US$57
12/10
No data
Today
No data
14/10
No data
15/10
No data
16/10
No data
17/10
No data
18/10
No data
busbud logoThe cheapest trip from Greenville, SC to Gainesville, FL was searched and found on 11 Oct 2025 with a price of US$57

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville, SC to Gainesville, FL as early as possible.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Greenville to Gainesville.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Greenville to Gainesville, get comfy and count the stars.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Greenville to Gainesville will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Tune out to the fine sounds of your best music playlist on your bus trip from Greenville to Gainesville while indulging in miles on end of beautiful scenic views.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

Will you be returning to Greenville, SC by bus?

Bus from Gainesville, FL to Greenville, SC

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

‌

Popular Buses Connecting Greenville

Buses Leaving from Greenville

Buses Going to Greenville

Popular Buses Connecting Gainesville

Buses Leaving from Gainesville

Buses Going to Gainesville