How can I travel from Greenville to Gainesville without flying?

Both buses and trains are available for traveling between these two cities. Both are convenient and sustainable ways to travel to Gainesville. Another option is using carpool services and riding with fellow travelers.

How long does it take to get to Gainesville from Greenville by bus?

Traveling from Greenville to Gainesville takes about 12h 10m on average, but the quickest bus can get you there in about 9h 15m. This is the time it takes to travel the 359 miles (579 km) that separate the two cities.

What is the travel distance from Greenville to Gainesville?

Greenville and Gainesville are 359 miles (579 km) apart.

What are the departure and arrival stations when taking the bus from Greenville to Gainesville?

The majority of buses traveling from Greenville to Gainesville start their journey at Guadalajara Supermarket Bus Stop and wind up at Rosa Parks Station. These are the most popular departure and arrival locations on this route, but you can also find other options that could better fit your plans.

What is the most affordable way to get from Greenville to Gainesville?

If you want the cheapest way to travel this route, take the bus. With prices starting at $49, you won't find a cheaper way to get there.

How much are the bus tickets from Greenville to Gainesville?

The bus ticket costs $89 on average. In the last 30 days, the prices ranged from $49 to $263, so it's good to do your research before booking.

Greenville (SC) to Gainesville (FL) Bus Tickets

Compare 2 ways to go from Greenville to Gainesville.

	Average Price	Average Duration	CO₂ emissions
Bus	Average Price$49 - $263	Average Duration12h 10m	CO₂ emissions 14kg CO₂e5 out of 5 stars	CheapestFastestMost eco-friendly
Train	Average Price$159 - $175	Average Duration1d 6h	CO₂ emissions 52kg CO₂e1 out of 5 stars

Busbud recommends taking the bus from Greenville to Gainesville

Among the sustainable travel choices, the bus stands out as the good way to reach Gainesville. The journey takes about 12 hours 10 minutes and with fares starting at just $49, it presents an excellent value for a comfortable ride.

6bus per day

12h 10mAverage Duration

$49Cheapest ticket

14kgCO₂ emissions

Bus Greenville to Gainesville: Trip Overview

Average ticket price$89

Average bus trip duration12h 10m

Number of daily buses6

Earliest bus departure8:25am

Distance353 miles (569 km)

Latest bus departure10:00pm

Compare bus companies

FlixBus

3.5/58,716 reviews

Staff4.1

Timeliness4

Cleanliness4.1

Wifi2.6

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Tornado Bus

3/5127 reviews

Staff5

Timeliness1.7

Cleanliness5

Wifi2.5

A Texas-based company, Tornado Bus operates throughout the United States, with routes connecting major cities, including Houston, San Antonio and El Paso. Each day,1 buses leave from their terminals to destinations across the continent. Their buses are equipped with free Wi-Fi, air conditioning, bathrooms, power outlets and a comfortable amount of legroom. With prices as low as $263.00 for a short ride, Tornado offers options for budget travelers, without compromising comfort. and those looking for a little luxury. The company requires printed tickets for boarding and their tickets are non-refundable, but you can exchange them up to two hours before travel time for a fee. With a friendly staff and multiple routes, traveling with Tornado is a convenient way to get around.

Greyhound

3.5/586,996 reviews

Staff3.6

Timeliness2.8

Cleanliness3.3

Wifi2.3

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

US bus companies: FlixBus, Greyhound, Tornado Bus, Los Limousines, Valley Transit, Tufesa, Wanda Coach

Greenville to Gainesville Bus

With Busbud, comparing and booking tickets for a bus from Greenville to Gainesville is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from Greenville to Gainesville from the most reliable bus companies operating this trip.

Discover how much the bus trip from Greenville to Gainesville will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Where are the popular stops in Greenville and Gainesville?

Stops in Greenville

A - Guadalajara Supermarket Bus Stop

B - Greenville Bus Station

Stops in Gainesville

A - Rosa Parks Station

B - Williston Rd & I-75

C - Greyhound Station

Frequently asked questions for your trip Greenville (SC) - Gainesville (FL)

How can I travel from Greenville to Gainesville without flying?
How long does it take to get to Gainesville from Greenville by bus?
What is the travel distance from Greenville to Gainesville?
What are the departure and arrival stations when taking the bus from Greenville to Gainesville?
What is the most affordable way to get from Greenville to Gainesville?
How much are the bus tickets from Greenville to Gainesville?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

05/20

No data

05/21

$132

Today

No data

05/23

$73

05/24

No data

05/25

No data

05/26

No data

05/27

No data

The cheapest trip from Greenville to Gainesville was searched and found on May 23, 2025 with a price of $73

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville to Gainesville, as early as possible.

You can expect to pay from $73 to $250 for a bus ticket from Greenville to Gainesville based on the last 2 days. You can expect to find the cheapest price for the trip at $73 which is on 2025-05-23.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Greenville to Gainesville.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Greenville to Gainesville, get comfy and count the stars.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Greenville to Gainesville will emit less CO2 than a car or an airplane.

Tune out to the fine sounds of your best music playlist on your bus trip from Greenville to Gainesville while indulging in miles on end of beautiful scenic views.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

What's the cheapest way to go from Greenville to Gainesville?

The bus is the cheapest travel choice for this destination

Vehicle Type	Travel Time	Avg Price	Daily Departures
Vehicle TypeBus	Travel Time12h 10m	Avg Price$89	Daily Departures6
Vehicle TypeTrain	Travel Time1d 6h	Avg Price$175	Daily Departures1

Will you be returning to Greenville by bus?

Bus from Greenville to Gainesville

You can also go to Gainesville by train

Train from Greenville to Gainesville

Top traveled bus routes

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

Bus Tickets from Greenville (SC) to Gainesville (FL)

Compare 2 ways to go from Greenville to Gainesville.

Bus Greenville to Gainesville: Trip Overview

Compare bus companies

Greenville to Gainesville Bus

Where are the popular stops in Greenville and Gainesville?

Frequently asked questions for your trip Greenville (SC) - Gainesville (FL)

How can I travel from Greenville to Gainesville without flying?

How long does it take to get to Gainesville from Greenville by bus?

What is the travel distance from Greenville to Gainesville?

What are the departure and arrival stations when taking the bus from Greenville to Gainesville?

What is the most affordable way to get from Greenville to Gainesville?

How much are the bus tickets from Greenville to Gainesville?

Find cheapest prices for buses

About Bus Travel

Bus Travel Tips

Did you know?

What's the cheapest way to go from Greenville to Gainesville?

Will you be returning to Greenville by bus?

You can also go to Gainesville by train

Top traveled bus routes

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

People from around the world trust Busbud

Popular Buses Connecting Greenville

Buses Leaving from Greenville

Buses Going to Greenville

Popular Buses Connecting Gainesville

Buses Leaving from Gainesville

Buses Going to Gainesville

Popular routes in this country

Popular airport transfers