Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | Indianapolis Bus Station | 409 Townsend St, SF | Cheapest | ||||
 | Bus | Indianapolis Bus Station | San Francisco Bus Station | Fastest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Indianapolis Bus Station | 409 Townsend St, SF | No tags | ||||
| Bus | Indianapolis Bus Station | San Francisco Bus Station | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Indianapolis Bus Station | 409 Townsend St, SF | No tags |
Last refresh of the prices: Last Thursday at 06:10 EST.
Get from Indianapolis to San Francisco
The journey takes about 2 days, 15 hours 50 minutes, and with fares starting at just £103, it presents an excellent value for a comfortable ride.
Where are the popular stops in Indianapolis and San Francisco?
Stops in Indianapolis
- A350 S Illinois St, Indianapolis, IN 46225
Stops in San Francisco
- A
Hyde/Beach (Fisherman's Wharf)
700 Beach Street, San Francisco, CA 94109, USA - B
Powell Station
25 Cyril Magnin St , San Francisco, CA 94102-2812 - C
Union Square Hilton
255 Mason St,, San Francisco, CA 94102-2114 - D
San Francisco Greyhound Station
200 Folsom St, San Francisco, CA 94105 - E
444 Townsend St.
444 Townsend St, San Francisco, CA 94107, USA
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Frequently asked questions about travelling by bus from Indianapolis to San Francisco, US
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Indianapolis to San Francisco?
The cheapest coach tickets from Indianapolis to San Francisco start from £103. The average price for this route is around £287. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Indianapolis to San Francisco?
The average bus journey time from Indianapolis to San Francisco is 2d 15h, covering a distance of 1940 miles. The fastest bus can take you there in 2d 5h and is operated by Greyhound.
Which bus companies service the Indianapolis to San Francisco route?
What is the earliest and latest departure time for the bus from Indianapolis to San Francisco?
The earliest bus departs from Indianapolis to San Francisco at 05:00. And the latest bus departs at 23:30.
What are the CO₂ emissions for the bus trip from Indianapolis to San Francisco?
A bus journey from Indianapolis to San Francisco produces an estimated 78 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Which is the best bus company from Indianapolis to San Francisco?
According to Busbud customers, the highest-rated bus company on this route is Amtrak, with an average rating of 4.1 out of 5 stars based on 5733 reviews.
Which company has the best Wi-Fi from Indianapolis to San Francisco?
Based on Busbud reviews, the bus company Amtrak has the best Wi-Fi rating with a score of 3.6.
Which bus company offers the most punctual service from Indianapolis to San Francisco?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Indianapolis to San Francisco?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Amtrak, with a cleanliness rating of 4.5 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Indianapolis to San Francisco, US was searched and found on 19 Jan 2026 with a price of £163To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Indianapolis to San Francisco, US as early as possible.
You can expect to pay from £163 to £403 for a bus ticket from Indianapolis to San Francisco, US based on the last 2 days. You can expect to find the cheapest price for the trip at £163, which is on 2026-01-19.
