Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Jacksonville Bus Station | Port St. Lucie (Park & Ride) | Cheapest | ||||
 | Bus | Jacksonville Bus Station | Port St. Lucie (Park & Ride) | Fastest | ||||
| Bus | Jacksonville Bus Station | Port St. Lucie (Park & Ride) | No tags |
Last refresh of the prices: Yesterday at 23:00 EST.
Get from Jacksonville to Port Saint Lucie
The journey takes about 6 hours 40 minutes, and with fares starting at just £32, it presents an excellent value for a comfortable ride.
Where are the popular stops in Jacksonville and Port Saint Lucie?
Stops in Jacksonville
- A3570 Clifford Ln, Jacksonville, FL 32209, USA
- B
W Forsyth St
1111 W Forsyth St, Jacksonville, FL 32204, USA - C
Kings Avenue Station
1003 Kings Avenue, Jacksonville, FL 32207 - D
JRTC Greyhound Bus Station
111 W. Forsyth St, Jacksonville, FL 32202, USA
Stops in Port Saint Lucie
- A
Port St Lucie Mobil Gas Bus Stop
1820 Sw Fountainview Blvd, Port Saint Lucie, FL 34986 - B
Port Saint Lucie - Wendys
1790 SW St Lucie W Blvd, Port St Lucie, FL 34986 - C
Port Saint LucieService Plaza
Florida's Turnpike, Milepost 144, Port St Lucie, FL 34984, USA - D
Port Saint Lucie Bus Stop
2198 SW Gatlin Blvd. Port St. Lucie, FL 34953
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Frequently asked questions about travelling by bus from Jacksonville, FL to Port Saint Lucie
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Jacksonville to Port Saint Lucie?
The cheapest coach tickets from Jacksonville to Port Saint Lucie start from £32. The average price for this route is around £44. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Jacksonville to Port Saint Lucie?
The average bus journey time from Jacksonville to Port Saint Lucie is 6h 40m, covering a distance of 225 miles. The fastest bus can take you there in 6h 5m and is operated by FlixBus.
Which bus companies service the Jacksonville to Port Saint Lucie route?
What is the earliest and latest departure time for the bus from Jacksonville to Port Saint Lucie?
The earliest bus departs from Jacksonville to Port Saint Lucie at 09:00. And the latest bus departs at 21:10.
What are the CO₂ emissions for the bus trip from Jacksonville to Port Saint Lucie?
A bus journey from Jacksonville to Port Saint Lucie produces an estimated 9 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Which is the best bus company from Jacksonville to Port Saint Lucie?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 11504 reviews.
Which company has the best Wi-Fi from Jacksonville to Port Saint Lucie?
Based on Busbud reviews, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from Jacksonville to Port Saint Lucie?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Jacksonville to Port Saint Lucie?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Jacksonville, FL to Port Saint Lucie was searched and found on 7 Dec 2025 with a price of £29To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Jacksonville, FL to Port Saint Lucie as early as possible.
You can expect to pay from £29 to £80 for a bus ticket from Jacksonville, FL to Port Saint Lucie based on the last 2 days. You can expect to find the cheapest price for the trip at £29, which is on 2025-12-07.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
