Find coaches from Jacksonville, FL to Spartanburg

Find affordable coach tickets from Jacksonville, FL to Spartanburg with flexible options. Book your journey now

Join 75M+ travellers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every stage.
Cancel anytime and receive a 100% refund, no reason needed.
Today26 Jul
from US$139
Tomorrow27 Jul
Mon28 Jul
Tue29 Jul
Wed30 Jul
Thu31 Jul
Fri1 Aug
from US$97
Sat2 Aug
from US$104

Cheap buses leaving Friday

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: 1 August at
    Departure city: Jacksonville
    Departure location: Jacksonville Bus Station
    Arrival time: 1 August at
    Destination city: Spartanburg
    Destination location: Spartanburg
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: 1 August at
    Departure city: Jacksonville
    Departure location: Jacksonville Bus Station
    Arrival time: 2 August at
    Destination city: Spartanburg
    Destination location: Spartanburg
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 1 August at
    Departure city: Jacksonville
    Departure location: Jacksonville Bus Station
    Arrival time: 2 August at
    Destination city: Spartanburg
    Destination location: Spartanburg
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 1 August at
    Departure city: Jacksonville
    Departure location: Jacksonville Bus Station
    Arrival time: 2 August at
    Destination city: Spartanburg
    Destination location: Spartanburg
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to travel from Jacksonville to Spartanburg

Average priceUS$70 - US$222Average duration15h 20m
13kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Average priceUS$136 - US$1,400Average duration1d 5h
46kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Jacksonville to Spartanburg

Among the sustainable travel choices, the bus stands out as a good way to reach Spartanburg. The journey takes about 15 hours 20 minutes and with fares starting at just US$70, it presents an excellent value for a comfortable ride.

3bus per day
15h 20mAverage duration
US$70Cheapest ticket
13kgCO₂ emissions

Bus Jacksonville, FL to Spartanburg: Trip Overview

Average ticket priceUS$125
Average bus trip duration15h 20m
Number of daily buses3
Earliest bus departure08:05
Distance323 miles
Latest bus departure21:45

Jacksonville to Spartanburg Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Jacksonville to Spartanburg.

We make sure you can find a bus service from Jacksonville to Spartanburg from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Spartanburg from Jacksonville, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Jacksonville, FL - Spartanburg

  1. How far is Spartanburg from Jacksonville by coach?

    The distance between Jacksonville and Spartanburg by coach is approximately 320 miles (515 km).

  2. What is the best way to go from Jacksonville to Spartanburg without flying?

    You have the option to select the coach for your journey on this route. The coach ensures a pleasant travel experience, granting you the opportunity to appreciate the scenery as you make your way to your final stop. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
24/07
No data
25/07
No data
Today
US$134
27/07
No data
28/07
No data
29/07
No data
30/07
No data
31/07
No data
busbud logoThe cheapest trip from Jacksonville, FL to Spartanburg was searched and found on 26 Jul 2025 with a price of US$134

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Jacksonville, FL to Spartanburg as early as possible.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Jacksonville to Spartanburg but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Jacksonville to Spartanburg, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Jacksonville to Spartanburg.

Make a music playlist for your bus ride from Jacksonville to Spartanburg, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

What's the cheapest way to go from Jacksonville, FL to Spartanburg?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Jacksonville, FL by bus?

Bus from Jacksonville, FL to Spartanburg

You can also go to Spartanburg by train

Train from Jacksonville, FL to Spartanburg

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

Popular bus departures from Jacksonville

Popular bus departures to Jacksonville

Continue your journey from Spartanburg