Previously seen journeys
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound | Bus | Knoxville Bus Station | Rosa Parks Station | No tags | ||||
Greyhound + FlixBus | Bus | Knoxville Bus Station | Rosa Parks Station | No tags | ||||
 | Bus | Knoxville Bus Station | Gainesville Bus Stop | No tags | ||||
| Bus | Knoxville Bus Station | Gainesville Bus Stop | No tags | ||||
Greyhound + FlixBus | Bus | Knoxville Bus Station | Rosa Parks Station | No tags |
Get from Knoxville to Gainesville
The journey takes about 16 hours 55 minutes, and with fares starting at just £67, it presents an excellent value for a comfortable ride.
Where are the popular stops in Knoxville and Gainesville?
Stops in Knoxville
- AKnoxville Area Transit Bus Stop, 100 Kirkwood St, Knoxville, TN 37914, USA
Stops in Gainesville
- A700 SE 3rd St, Gainesville, FL 32601
- B3509 SW Williston Rd, Gainesville, FL 32608, USA
- C101 NE 23rd Ave, Gainesville, FL 32609
Compare bus companies
Based on 87501 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. Greyhound ticket prices on this trip start at £67
Frequently asked questions about travelling by bus from Knoxville, TN to Gainesville, FL
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Knoxville to Gainesville?
The cheapest coach tickets from Knoxville to Gainesville start from £67. The average price for this route is around £107. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Knoxville to Gainesville?
The average bus journey time from Knoxville to Gainesville is 16h 55m, covering a distance of 448 miles. The fastest bus can take you there in 11h 20m and is operated by Greyhound.
Which bus companies service the Knoxville to Gainesville route?
Several major bus companies operate on this route with 2 buses available per day.
What is the earliest and latest departure time for the bus from Knoxville to Gainesville?
The earliest bus departs from Knoxville to Gainesville at 18:10. And the latest bus departs at 19:40.
What are the CO₂ emissions for the bus trip from Knoxville to Gainesville?
A bus journey from Knoxville to Gainesville produces an estimated 18 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Knoxville, TN to Gainesville, FL was searched and found on 15 Jan 2026 with a price of £103To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Knoxville, TN to Gainesville, FL as early as possible.
