- Knoxville to Gainesville buses
Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
![]() | Bus | Knoxville Bus Station | Gainesville Bus Stop | No tags | ||||
![]() | Bus | Knoxville Bus Station | Gainesville Bus Stop | No tags | ||||
FlixBus + Greyhound | Bus | Knoxville Bus Station | Rosa Parks Station | No tags | ||||
Greyhound + FlixBus | Bus | Knoxville Bus Station | Rosa Parks Station | No tags | ||||
FlixBus + Greyhound | Bus | Knoxville Bus Station | Rosa Parks Station | No tags |
Get from Knoxville to Gainesville
The journey takes about 11 hours 20 minutes and with fares starting at just $56, it presents an excellent value for a comfortable ride.
Where are the popular stops in Knoxville and Gainesville?
Stops in Knoxville
- AKnoxville Area Transit Bus Stop, 100 Kirkwood St, Knoxville, TN 37914, USA
Stops in Gainesville
- A700 SE 3rd St, Gainesville, FL 32601
- B3509 SW Williston Rd, Gainesville, FL 32608, USA
- C101 NE 23rd Ave, Gainesville, FL 32609
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Knoxville, TN to Gainesville, FL by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Knoxville to Gainesville?
The cheapest bus tickets from Knoxville to Gainesville start from $56. The average price for this route is around $143. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Knoxville to Gainesville?
The average bus trip duration from Knoxville to Gainesville is 11h 20m, covering a distance of 443 miles (714 km). The quickest bus can get you there in 11h 20m and is operated by Greyhound.
Which bus companies service the Knoxville to Gainesville route?
Several major train operators operate on this route with 2 trains available per day.
What is the earliest and latest departure time for the bus from Knoxville to Gainesville?
The earliest bus departs from Knoxville to Gainesville at 7:05pm. And the latest bus departs at 7:05pm.
What are the CO₂ emissions for the bus trip from Knoxville to Gainesville?
A bus trip from Knoxville to Gainesville generates an estimated 18 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.






