Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Orlando Bus Station | Durham Greyhound Bus Station | CheapestFastest | ||||
| Bus | Orlando Bus Station | Durham Greyhound Bus Station | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Orlando Bus Station | Durham Greyhound Bus Station | No tags | ||||
 | Bus | Orlando Bus Station | Durham Greyhound Bus Station | No tags | ||||
| Bus | Orlando Bus Station | Durham Greyhound Bus Station | No tags |
Last refresh of the prices: Today at 16:49 EST.
Compare 2 ways to travel from Orlando to Durham
Among the sustainable travel choices, the train stands out as a good way to reach Durham. The journey takes about 15 hours 40 minutes and with fares starting at just £52, it presents an excellent value for a comfortable ride.
Where are the popular stops in Orlando and Durham?
Stops in Orlando
- A555 N John Young Pkwy, Orlando, FL 32805
- BRedCoach Station, 1777 McCoy Road, Orlando, FL 32809
- CJet Set Express Terminal, 3718 LB Mcleod Rd., 32805 Orlando, FL,, United States
- D
Disney World
Disney's All-Star Sports Resort, 1701 West Buena Vista Dr., Orlando, FL 32830 - E
International Dr SuperTours Terminal
5419 International Dr, Orlando, FL 32819, USA - F
Seaworld Hotels
10100 International Drive , Orlando, 32821
Stops in Durham
- A515 W Pettigrew St , Durham, NC 27703
- B
Compare Foods Durham
2000-2004 NC-55, Durham, NC 27704, USA - C
Durham Compare Foods Durham
2000 Avondale Dr, Durham, NC 27704, USA - D
Durham, NC
E Main St at Roxboro St (WB), Durham, NC 27701, USA
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Frequently asked questions about travelling by bus from Orlando to Durham, NC, US
What's the distance between Orlando and Durham by coach?
The journey from Orlando to Durham by coach covers an approximate distance of 535 miles (863 km).
How can I travel from Orlando to Durham avoiding air travel?
You can choose the coach to travel this route. The coach ensures a pleasant travel experience, granting you the opportunity to appreciate the scenery as you make your way to your final stop. You might also find carpooling options to travel between the two cities.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Orlando to Durham, NC, US was searched and found on 25 Nov 2025 with a price of £94To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Orlando to Durham, NC, US as early as possible.
You can expect to pay from £94 to £191 for a bus ticket from Orlando to Durham, NC, US based on the last 2 days. You can expect to find the cheapest price for the trip at £94, which is on 2025-11-25.
Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
